Español
العربية
Francés
Русский
Português
Deutsch
Italiano
Kazakh
Uzbek
Dihydromyricetin CAS#27200-12-0
CAS Number: 27200-12-0
Chemical Formula: C18H32O7
Synonyms:
3,3’,4’,5,5’,7-hexahydroxy-flavanon
2,3-dihydro-3,5,7-trihydroxy-2-(3,4,5-trihydroxyphenyl)-4h-1-benzopyran-4-on
MOQ (Minimum Order Quantity): 1 FCL (Full Container Load)
Appearance: White Powder
Dihydromyricetin CAS#27200-12-0
(+)-dihydromyricetin is an optically active form of dihydromyricetin having (2R,3R)-configuration. It has a role as a metabolite, an antioxidant and an antineoplastic agent. It is a secondary alpha-hydroxy ketone and a dihydromyricetin. It is an enantiomer of a (-)-dihydromyricetin.Dihydromyricetin (DHM), also known as ampelopsin, is a natural flavonoid compound, which is found in large quantities in Asian plant species. One of them – Hovenia dulcis – is known for centuries in traditional Chinese medicine as a cure for alcohol poisoning and hangover (Liang et al. 2014). DHM is sold as a supplement and is commonly marketed as a treatment for hangovers due to its ability to reduce blood alcohol levels and projected hepatoprotective properties.
Dihydromyricetin had beneficial effects on health such as antimicrobial, anti-inflammatory,antioxidative, anticancer, lipid and glucose metabolism-regulatory activities，and cell death-mediating without or with minimum adverse effects on normal cells. And most importantly, DHM has been shown to provide significant hepatoprotective effects. Its positive influence on alcohol-induced and other liver diseases was suggested in the study of acute liver failure (Liu et al. 2017).
Dihydromyricetin Chemical Properties |
storage temp. | -20°C |
solubility | DMSO: ≥5mg/mL (warmed) |
Melting point | 239-241 °C |
pKa | 7.38±0.60(Predicted) |
Boiling point | 780.7±60.0 °C(Predicted) |
density | 1.808±0.06 g/cm3(Predicted) |
form | powder |
color | white to beige |
Stability: | Hygroscopic |
Cosmetics Ingredients Functions | SKIN CONDITIONING |
InChI | InChI=1S/C15H12O8/c16-6-3-7(17)11-10(4-6)23-15(14(22)13(11)21)5-1-8(18)12(20)9(19)2-5/h1-4,14-20,22H/t14-,15+/m0/s1 |
InChIKey | KJXSIXMJHKAJOD-LSDHHAIUSA-N |
SMILES | [C@H]1(C2=CC(O)=C(O)C(O)=C2)OC2=CC(O)=CC(O)=C2C(=O)[C@@H]1O |
LogP | 1.230 (est) |
CAS DataBase Reference | 27200-12-0 |
Safety Information |
Safety Statements | 24/25 |
WGK Germany | 3 |
HS Code | 29329990 |
Storage Class | 11 - Combustible Solids |
Product Application of Dihydromyricetin CAS#27200-12-0
Dihydromyricetin has been used to study its effect on adipogenesis and glucose uptake in differentiated 3T3-L1 pre-adipocytes. It has also been used to study its antitumor activity against liver cancer cells.
Fact Factory and Equipment Show
Fast delivery time
Inventory 2-3 working days New production 7-10 working days
