Dihydromyricetin CAS#27200-12-0

CAS Number: 27200-12-0
Chemical Formula: C22H17Cl2F6N3O3
Synonyms:

2,3-dihydro-3,5,7-trihydroxy-2-(3,4,5-trihydroxyphenyl)-4h-1-benzopyran-4-on
3,3’,4’,5,5’,7-hexahydroxy-2,3-dihydroflavanonol
3,3’,4’,5,5’,7-hexahydroxy-flavanon

Appearance: White Powder

MOQ (Minimum Order Quantity): 1 FCL (Full Container Load)

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Product Details

Dihydromyricetin CAS#27200-12-0

Dihydromyricetin (DHM), also known as ampelopsin, is a natural flavonoid compound, which is found in large quantities in Asian plant species. One of them – Hovenia dulcis – is known for centuries in traditional Chinese medicine as a cure for alcohol poisoning and hangover (Liang et al. 2014). DHM is sold as a supplement and is commonly marketed as a treatment for hangovers due to its ability to reduce blood alcohol levels and projected hepatoprotective properties.
Dihydromyricetin had beneficial effects on health such as antimicrobial, anti-inflammatory,antioxidative, anticancer, lipid and glucose metabolism-regulatory activities，and cell death-mediating without or with minimum adverse effects on normal cells. And most importantly, DHM has been shown to provide significant hepatoprotective effects. Its positive influence on alcohol-induced and other liver diseases was suggested in the study of acute liver failure (Liu et al. 2017).

Dihydromyricetin Chemical Properties

storage temp.	-20°C
solubility	DMSO: ≥5mg/mL (warmed)
Melting point	239-241 °C
pKa	7.38±0.60(Predicted)
Boiling point	780.7±60.0 °C(Predicted)
density	1.808±0.06 g/cm3(Predicted)
form	powder
color	white to beige
Stability:	Hygroscopic
Cosmetics Ingredients Functions	SKIN CONDITIONING
InChI	InChI=1S/C15H12O8/c16-6-3-7(17)11-10(4-6)23-15(14(22)13(11)21)5-1-8(18)12(20)9(19)2-5/h1-4,14-20,22H/t14-,15+/m0/s1
InChIKey	KJXSIXMJHKAJOD-LSDHHAIUSA-N
SMILES	[C@H]1(C2=CC(O)=C(O)C(O)=C2)OC2=CC(O)=CC(O)=C2C(=O)[C@@H]1O
LogP	1.230 (est)
CAS DataBase Reference	27200-12-0

Safety Information

Safety Statements	24/25
WGK Germany	3
HS Code	29329990
Storage Class	11 - Combustible Solids

Product Application of Dihydromyricetin CAS#27200-12-0

Dihydromyricetin can be used as a novel anti-alcoholism drug, clinically used to treat hangovers, fever, parasitic infections and liver disease. It is currently being studied in clinical trials for its effects on glycaemic control, insulin sensitivity and insulin secretion in type 2 diabetes.

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