Baicalin CAS#21967-41-9

CAS Number: 21967-41-9
Chemical Formula: C21H18O11
Synonyms:

BAICALEIN 7-BETA-D-GLUCOPYRANOSIDURONATE HYDRATE
BAICALIN 7-BETA-D-GLUCOPYRANOSIDURONATE HYDRATE
BAICALIN HYDRATE

Appearance: Light yellow Powder

MOQ (Minimum Order Quantity): 1 FCL (Full Container Load)

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Product Details

Baicalin CAS#21967-41-9

Baicalin, the active compound of the Blue Skullcap, is a type of flavonoid.
Baicalin exhibits anti-inflammatory, anti-tumor, anti-angiogenic, anti-oxidant, anti-apoptotic, anti-viral, and antibacterial properties. It could be used for the treatment of autoimmune diseases and several cancers (hepatitis B virus (HBV)-infected liver cancer, hepatic cancer, cervical cancer, etc.). It can be used to treat against dengue virus. It is used in preparation of the drug for treating and rescuing ricin poisoning. Due to its anti-apoptotic effect which can protect PC-12 cells from oxidative stress, baicalin can be used for reducing stress and helping to promote healthy sleep cycles.

Baicalin Chemical Properties

Melting point	202-205 °C (dec.) (lit.)
alpha	-85 º (c=1, DMSO)
Boiling point	836.6±65.0 °C(Predicted)
density	1.737±0.06 g/cm3(Predicted)
storage temp.	2-8°C
solubility	DMSO (Slightly), Methanol (Slightly)
pka	2.72±0.70(Predicted)
form	solid
color	Pale Yellow to Yellow
Optical Rotation	[α]20/D 85°, c = 1 in DMSO
Stability:	Hygroscopic
Cosmetics Ingredients Functions	SKIN CONDITIONING ANTIOXIDANT
InChIKey	IKIIZLYTISPENI-ZFORQUDYSA-N
SMILES	OC1C(=C(O[C@H]2[C@@H]([C@@H](O)[C@H](O)[C@@H](C(=O)O)O2)O)C=C2OC(C3C=CC=CC=3)=CC(=O)C=12)O \|&1:5,6,7,9,11,r\|
LogP	1.431 (est)
CAS DataBase Reference	21967-41-9(CAS DataBase Reference)

Safety Information

Hazard Codes	Xi
Risk Statements	36/37/38
Safety Statements	26-36
WGK Germany	3
RTECS	LZ5776910
HS Code	29329990
Storage Class	11 - Combustible Solids
Hazard Classifications	Acute Tox. 4 Oral

Product Application of Baicalin CAS#21967-41-9

In clinical, baicalin is mainly used as the adjuvant therapy for acute and chronic hepatitis and persistent hepatitis. Baicalin was shown to reduce the expression of hepatitis B surface antigen, e antigen and the core antigen, and inhibited hepatitis B virus DNA replication. Reduced serum alanine aminotransferase level was observed in hepatitis patient treated with baicalin, and other liver function indexes were also found to be improved. No adverse reactions about baicalin have been reported. In addition, baicalin was reported to treat early diabetic nephropathy and alleviate the symptoms of diabetic neuropathy
As one of the antimicrobial components of Scutellaria baicalensis, eye drops containing 3% baicalin are used clinically in the treatment of trachoma, with the similar curative effect as rifampicin.
Moreover, baicalein is used clinically for the treatment of enteritis and dysentery.

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