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Rifampicin CAS#13292-46-1

CAS Number:13292-46-1

Chemical Formula:C43H58N4O12

Synonyms:

RIFAMPIN ''LEPETIT''

8-(n-(4-methyl-1-piperazinyl)formidoyl)-rifomycins

8-(4-Methylpiperazinyliminomethyl)rifamycinSV

Appearance: Red crystal

HS Code:29419000

MOQ (Minimum Order Quantity): 1 FCL (Full Container Load)

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Product Details

Products Description of Rifampicin CAS#13292-46-1

Rifampicin (also translated as: rifamycin, mepiramycin, mepiramycin, Weifuxian, Sandaolun, Lifuping or Limidin, INN: Rifampicin) is a broad-spectrum antibiotic drug belonging to the rifamycin family. It has a strong antibacterial effect on Mycobacterium tuberculosis Chemicalbook, and is also effective against Gram-positive or negative bacteria, viruses, etc. It is a red or dark red crystalline powder that is insoluble in water. It is generally an oral capsule or tablet. It is used in combination with other anti-tuberculosis drugs to have a synergistic effect and delay the production of drug-resistant strains.

Parameters

Melting point	183°C (dec.)
Boiling point	761.02°C (rough estimate)
density	1.1782 (rough estimate)
refractive index	1.6000 (estimate)
storage temp.	2-8°C
solubility	chloroform: soluble50mg/mL, clear
pka	1.7, 7.9(at 25℃)
form	crystalline
color	faint red to very dark red
Water Solubility	Soluble in DMSO or methanolSoluble in water, ethyl acetate, chloroform, methanol, tetrahydrofuran and dimethyl sulfoxide.
Merck	148216
BRN	5723476
Specific Activity	Antibacterial
BCS Class	2
Stability:	Hygroscopic, Light Sensitive
IARC	3 (Vol. 24, Sup 7) 1987
EPA Substance Registry System	Rifampin (13292-46-1)
Safety Information
Hazard Codes	Xn,Xi
Risk Statements	22-36/37/38-36/38
Safety Statements	26-36-37/39
WGK Germany	3
RTECS	VJ7000000
F	39742
HS Code	29419000
Hazardous Substances Data	13292-46-1(Hazardous Substances Data)
Toxicity	LD50 in mice, rats (mg/kg): 885, 1720 orally; 260, 330 i.v.; 640, 550 i.p. (Fürész)

Product Application of Rifampicin CAS#13292-46-1

Broad-spectrum antibiotics. It has antibacterial or bactericidal effects on Mycobacterium tuberculosis, Gram-positive bacteria and some Gram-negative bacteria. It is mainly used for infections with drug-resistant tuberculosis bacteria and drug-resistant Staphylococcus aureus, and it also has a certain effect on leprosy. It is a broad-spectrum antibiotic and can enter the cell. Chemicalbook, it is a full-effect bactericidal drug with strong bactericidal power. It is a broad-spectrum antibiotic with strong bactericidal effects on mycobacteria and Gram-positive and negative bacteria. It is used as a pharmaceutical intermediate with a broad-spectrum antibacterial effect, and has good antibacterial activity against Gram-positive cocci and Mycobacterium tuberculosis. The antibacterial spectrum is the same as that of rifampicin.

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