Tween 80 CAS#9005-65-6

CAS Number: 9005-65-6
Chemical Formula: C24H44O6
Synonyms:

CHROMOGENIC SELECTIVE E.COLI 55MM
TRYPTONE SOY BROTH 120X15ML
TRYPTONE SOY BROTH 20X15ML

Appearance: Light Yellow Liquid

MOQ (Minimum Order Quantity): 1 FCL (Full Container Load)

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Product Details

Tween 80, commonly known as polysorbate 80, is a synthetic compound that is widely applied in a variety of fields, including foods, medicines, and cosmetics. In food production, it is commonly used as a defoamer for the fermenting process of some wines and as a emulsifier in ice-cream or “puddings” to keep the creamy texture without separating. Tween 80 is also extensively applied in pharmaceutical industry, where it can be found in some vaccines, vitamins and supplements. It is an effective excipient to stabilize aqueous formulations of medications for parenteral administration and to improve the consistency of gel capsules, thus to make pills disperse in the stomach. Besides, it commonly serve as a surfactant and solubilizer in the production of soaps and cosmetics, which is effective to help dissolve ingredients and make products look creamier and more attractive. In laboratory, it is occasionally used for a test to identify the phenotype of a strain or isolate, such as mycobacteria.

Tween 80 Chemical Properties

Melting point	-25 °C
Boiling point	>100°C
density	1.08 g/mL at 20 °C
vapor pressure	<1 mm Hg ( 20 °C)
refractive index	n20/D 1.473
FEMA	2917 \| POLYSORBATE 80
Fp	>230 °F
storage temp.	-20°C
solubility	DMSO (Soluble), Methanol (Slightly)
form	viscous liquid
color	Amber
Specific Gravity	1.080 (25/4℃)
PH	5-7 (50g/l, H2O, 20℃)
PH Range	6
Odor	mild alcoholic
Odor Type	alcoholic
biological source	synthetic
Water Solubility	5-10 g/100 mL at 23 ºC
Merck	14,7582
Hydrophilic-Lipophilic Balance (HLB)	10
Major Application	(ELISA and immunoassays)
Cosmetics Ingredients Functions	CLEANSING SURFACTANT - EMULSIFYING DENATURANT EMULSION STABILISING SURFACTANT - CLEANSING
Cosmetic Ingredient Review (CIR)	Tween 80 (9005-65-6)
InChIKey	RGPBUVUVZKQNHD-MDZDMXLPSA-N
SMILES	CCCCCCCC/C=C/CCCCCCCC(=O)OCCOCC(C1C(CC(O1)OCCO)OCCO)OCCO
LogP	4.392 (est)
EPA Substance Registry System	Polysorbate 80 (9005-65-6)

Safety Information

Hazard Codes	Xi
Risk Statements	22-36/37/38-37/38-41
Safety Statements	24/25-36/37/39-36-26
WGK Germany	1
RTECS	WG2934000
F	3
TSCA	TSCA listed
HS Code	34021300
Storage Class	10 - Combustible liquids
Hazardous Substances Data	9005-65-6(Hazardous Substances Data)
Toxicity	LD50 in mice, rats (ml/kg): 7.5, 6.3 i.p. (Varma)

Product Application of Tween 80 CAS#9005-65-6

Tween 80 is the trade name of a detergent that can be useful in identifying mycobacteria that possess a lipase that splits the compound into oleic acid and polyoxyethylated sorbitol.
Tween 80 is used as an additive for cell culture media. It has numerous effects, e.g. increasing the transformation frequency of Brevibacterium lactofermentum or enhancing the secretion of acid and alkaline phosphatase by Neurospora crassa.

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