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Resveratrol CAS#501-36-0
CAS Number: 501-36-0
Chemical Formula: C14H12O3
Synonyms:
3,4',5-TRIHYDROXY-TRANS-STILBENE
3,4',5'-TRIHYDROXY-TRANS-STILBENE
RESVERATROL;RESVERATROLE
MOQ (Minimum Order Quantity): 1 FCL (Full Container Load)
Appearance: White Powder
Resveratrol CAS#501-36-0
Resveratrol is a stilbenol that is stilbene in which the phenyl groups are substituted at positions 3, 5, and 4' by hydroxy groups. It has a role as a phytoalexin, an antioxidant, a glioma-associated oncogene inhibitor and a geroprotector. It is a stilbenol, a polyphenol and a member of resorcinols.Resveratrol, a non-flavonoid polyphenolic compound, is widely found in the skin of red grapes, nuts, berries, Polygonum cuspidatum root, etc. It is reportedly known to exhibit pharmacological properties including anti-cancer, anti-inflammatory, antioxidant, neuroprotectant, anti-atherogenic property and reduces the synthesis of pro-atherosclerotic substances.
| Resveratrol Chemical Properties |
| Melting point | 253-255°C |
| Boiling point | 449.1±14.0 °C(Predicted) |
| density | 1.359±0.06 g/cm3(Predicted) |
| storage temp. | -20°C |
| solubility | Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 20 mg/ml). |
| pka | 9.22±0.10(Predicted) |
| form | Powder |
| color | Off-white |
| biological source | plant root (bushy knotweed) |
| Water Solubility | Soluble in water (3 mg/100mL), ethanol (50 mg/mL), DMSO (16 mg/mL), DMF (~65 mg/mL), PBS (pH 7.2) (~100µg/mL), methanol, and acetone (50 mg/mL). |
| Merck | 14,8158 |
| Stability: | Stable for 2 years as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 month. |
| Cosmetics Ingredients Functions | SKIN PROTECTING ANTIOXIDANT |
| InChI | InChI=1S/C14H12O3/c15-12-5-3-10(4-6-12)1-2-11-7-13(16)9-14(17)8-11/h1-9,15-17H/b2-1+ |
| InChIKey | LUKBXSAWLPMMSZ-OWOJBTEDSA-N |
| SMILES | C1(O)=CC(/C=C/C2=CC=C(O)C=C2)=CC(O)=C1 |
| LogP | 3.139 (est) |
| CAS DataBase Reference | 501-36-0(CAS DataBase Reference) |
| EPA Substance Registry System | 1,3-Benzenediol, 5-[(1E)-2-(4-hydroxyphenyl)ethenyl]- (501-36-0) |
| Safety Information |
| Hazard Codes | Xi |
| Risk Statements | 37/38-41-36/38-36-43-22 |
| Safety Statements | 26-39-37/39-36/37/39 |
| WGK Germany | 3 |
| RTECS | CZ8987000 |
| HS Code | 29072990 |
| Hazardous Substances Data | 501-36-0(Hazardous Substances Data) |
Product Application of Resveratrol CAS#501-36-0
Resveratrol is a natural antioxidant. It reduces blood viscosity, inhibits platelet aggregation and vasodilation, keeps blood flowing smoothly, and prevents the occurrence and development of cancer. It has the effect of preventing and treating atherosclerosis, coronary heart disease, ischemic heart disease and hyperlipidemia. It has tumor-inhibiting effects. Resveratrol also has estrogen-like effects and can be used to treat breast cancer and other diseases. It slows down aging and prevents cancer. Red grape skins, red wine and grape juice contain high concentrations of resveratrol. Studies have shown that as humans age, the integrity of chromosomes is disrupted. However, resveratrol activates proteins that can repair chromosomes, thus slowing down aging.
Resveratrol is effective in preventing aging, in part due to its antioxidant properties, and is recommended for use in pre- or post-sun products. Resveratrol can cross the stratum corneum and be found in the dermis and epidermis. It has been shown to protect dermal collagen and may be effective in enhancing glycosaminoglycans, thereby improving tissue hydration. It has been shown to stimulate cell renewal in the skin and to help increase skin thickness. It has been shown to inhibit tyrosinase, which suggests it may be used to reduce hyperpigmentation.
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