Mannitol CAS#87-78-5

CAS Number: 87-78-5
Chemical Formula: C6H14O6
Synonyms:

MANNITOL PYROGEN FREE USP24
MANNITOL
DL-Mannitol

Appearance: White Powder

MOQ (Minimum Order Quantity): 1 FCL (Full Container Load)

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Product Details

Mannitol CAS#87-78-5

D-mannitol (D-mannohexan-1.2.3.4.5.6-hexaol) is a constituent of several plants including the Manna ash, several edible plants, and seaweed. Parts of the latter contain up to 10 % mannitol by weight. The solubility in water is approximately 230 g/L at room temperature and it increases with increasing temperature. Mannitol is stable under the common processing conditions of foods.
Mannitol is approximately 50 % as sweet as sucrose and non-cariogenic. In the European Union, maltitol is approved as E 421 for a large number of food applications. In the United States, mannitol produced by hydrogenation of glucose or fructose solutions or by fermentation by Zygosaccharomyces rouxii or Lactobacillus intermedius is approved for several food applications. It is also approved in many other countries.

Mannitol Chemical Properties

Melting point	167°C
Boiling point	494.9°C
density	1.596
refractive index	1.5970 (estimate)
storage temp.	Inert atmosphere,Room Temperature
pka	pKa 13.50(H2O,t =18)(Approximate)
form	Solid
color	White to off-white
Water Solubility	177.3g/L(25 ºC)
Dielectric constant	3.0（22℃）
InChI	InChI=1S/C6H14O6/c7-1-3(9)5(11)6(12)4(10)2-8/h3-12H,1-2H2/t3-,4-,5-,6-/m1/s1
InChIKey	FBPFZTCFMRRESA-KVTDHHQDSA-N
SMILES	OC[C@H]([C@H]([C@@H]([C@@H](CO)O)O)O)O
CAS DataBase Reference	87-78-5(CAS DataBase Reference)
EPA Substance Registry System	Mannitol (87-78-5)

Safety Information

TSCA	TSCA listed
HS Code	29054300

Product Application of Mannitol CAS#87-78-5

Mannitol is a good diuretic in medicine. It can reduce intracranial pressure, intraocular pressure, kidney medicine, dehydrating medicine, sugar substitute, excipient of tablets and diluent of solid and liquid. As a hypertonic antihypertensive drug, Injectio mannitou injection is commonly used in clinical rescue, especially in the rescue of brain diseases. It has the characteristics of fast antihypertensive and accurate curative effect required by drugs to reduce intracranial pressure. After mannitol enters the body, it can increase the plasma osmotic pressure, dehydrate the tissue, and reduce the intracranial pressure and intraocular pressure. After glomerular filtration, it is not easy to be reabsorbed by renal tubules, increase the urinary osmotic pressure, bring out a large amount of water and dehydrate. It is used for edema caused by craniocerebral trauma, brain tumor and brain tissue hypoxia, edema caused by large-area burn, ascites and glaucoma caused by renal failure. It can prevent and treat early acute renal insufficiency.

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