Sodium Citrate CAS#68-04-2
CAS Number: 68-04-2
Chemical Formula: C6H9NaO7
Synonyms:
1,2,3-propanetricarboxylicacid2hydroxy-trisodiumsalt
1,2,3-Propanetricarboxylicacid,2-hydroxy,trisodiumsalt
CITRIC ACID TRISODIUM SALT, VETEC
MOQ (Minimum Order Quantity): 1 FCL (Full Container Load)
Appearance: Transperant Liquid
Sodium Citrate CAS#68-04-2
Sodium citrate may refer to any of the sodium salts of citric acid (though most commonly the third):
Mono sodium citrate
Di sodium citrate
Tri sodium citrate
As food additives, the 3 forms of the salt are also collectively known by the E number E331.
Sodium citrate Chemical Properties |
Melting point | 300°C |
density | 1.008 g/mL at 20 °C |
FEMA | 3026 | SODIUM CITRATE |
storage temp. | 2-8°C |
solubility | Water (Slightly) |
form | Liquid |
color | White to off-white |
Odor | at 100.00?%. odorless |
PH | 8.59(1 mM solution);8.9(10 mM solution);9.04(100 mM solution);9.26(1000 mM solution) |
Water Solubility | Soluble in water. |
λmax | λ: 260 nm Amax: ≤0.1 |
Sensitive | Hygroscopic |
Stability: | Hygroscopic |
Cosmetics Ingredients Functions | CHELATING |
InChI | 1S/C6H8O7.3Na/c7-3(8)1-6(13,5(11)12)2-4(9)10;;;/h13H,1-2H2,(H,7,8)(H,9,10)(H,11,12);;;/q;3*+1/p-3 |
InChIKey | HRXKRNGNAMMEHJ-UHFFFAOYSA-K |
SMILES | [Na+].[Na+].[Na+].OC(CC([O-])=O)(CC([O-])=O)C([O-])=O |
LogP | -0.280 (est) |
CAS DataBase Reference | 68-04-2(CAS DataBase Reference) |
EPA Substance Registry System | Trisodium citrate (68-04-2) |
Safety Information |
Hazard Codes | Xi,C |
Risk Statements | 22-40-48/20/22-41-37/38-36-35 |
Safety Statements | 36-24/25-39-26-45-36/37/39 |
WGK Germany | 2 |
RTECS | GE8300000 |
F | 34 |
TSCA | TSCA listed |
HS Code | 29181500 |
Storage Class | 11 - Combustible Solids |
Hazardous Substances Data | 68-04-2(Hazardous Substances Data) |
Toxicity | LD50 in rats, mice (mmol/kg): 6.0, 5.5 i.p. (Gruber, Halbeisen) |
Product Application of Sodium Citrate CAS#68-04-2
2 – 1 - Food
Sodium citrate is chiefly used as a food additive E331, usually for flavor or as a preservative. Sodium citrate is employed as a flavoring agent in certain varieties of club soda. Sodium citrate is common as an ingredient in Bratwurst, and is also used in commercial ready to drink beverages and drink mixes, contributing a tart flavour.
2 – 2 - Buffer
As a conjugate base of a weak acid, citrate can perform as a buffering agent or acidity regulator, resisting changes in pH. Sodium citrate is used to control acidity in some substances, such as gelatin desserts. It can be found in the mini milk containers used with coffee machines. The compound is the product of antacids, such as Alka- Seltzer, when they are dissolved in water.
2 – 3 - Medical uses
In 1914, the Belgian doctor Albert Hustin and the Argentine physician and researcher Luis Agote successfully used sodium citrate as an anticoagulant in blood transfusions. It continues to be used today in blood collection tubes and for the preservation of blood in blood banks. The citrate ion chelates calcium ions in the blood by forming calcium citrate complexes, disrupting the blood clotting mechanism.
Sodium citrate is used to relieve discomfort in urinary tract infections, such as cystitis, to reduce the acidosis seen in distal renal tubular acidosis, and can also be used as an osmotic laxative. It is a major component of the WHO Oral Rehydration Solution.
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