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Streptomycin sulfate CAS#3810-74-0

CAS Number: 3810-74-0

Chemical Formula: C21H41N7O16S

Synonyms:

Streptomycin Sulfate (200 mg)

Streptomycin sulfate salt,Streptomycini sulfas

StreptoMycin sulphate inject grade

Appearance: White powder

HS Code:29412000

MOQ (Minimum Order Quantity): 1 FCL (Full Container Load)

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Product Details

Products Description of Streptomycin sulfate CAS#3810-74-0

Streptomycin sulfate is the sulfate form of streptomycin, an antibiotic produced by the soil actinomycete Streptomyces griseus. Streptomycin is the first chemotherapy drug to be developed that has a definite effect on tuberculosis. This product must be injected intramuscularly, so its long-term use is limited. Streptomycin is the most effective and least toxic antibiotic obtained from Streptomyces for extra-gastrointestinal use. This product is a bactericide, which may be effective by its direct effect on bacterial ribosomes and inhibiting protein synthesis. It mainly acts on extracellular (including cavitary) tuberculosis bacteria.

Parameters

Melting point	>185°C (dec.)
alpha	-79～-88°(20℃/D)(c=1,H2O)(calculated on the dried basis)
density	1.2302 (rough estimate)
refractive index	-85 ° (C=1, H2O)
storage temp.	2-8°C
solubility	H2O: 0.1 g/mL, clear
form	powder
color	white to off-white
PH	pH (100g/l, 25℃) : 4.5～7.0
Water Solubility	>=0.01 g/100 mL at 18 ºC
Merck	148826
BRN	3894995
Specific Activity	≥720IU/g (dry basis)
Stability:	Stable. Incompatible with strong oxidizing agents.
InChIKey	QTENRWWVYAAPBI-YZTFXSNBSA-N
LogP	-1.523 (est)
CAS DataBase Reference	3810-74-0
EPA Substance Registry System	Streptomycin sulfate (3810-74-0)
Safety Information
Hazard Codes	Xn,Xi
Risk Statements	22-36/37/38-63-42/43
Safety Statements	26-36-36/37-45-22-60
WGK Germany	3
RTECS	WK4990000
F	3
TSCA	Yes
HS Code	29412000

Product Application of Streptomycin sulfate CAS#3810-74-0

Streptomycin sulfate has antibacterial effects on most Gram-positive and Gram-negative bacteria, especially on a variety of Gram-negative bacteria such as Escherichia coli, Salmonella, Pasteurella, Brucella, Klebsiella pneumoniae, Shigella dysenteriae, Clostridium difficile, and Burkholderia thuringiensis. This product is the first choice for anti-tuberculosis bacteria. It has a strong effect on tuberculosis bacteria. It has a strong antibacterial effect at low concentrations and a bactericidal effect at high concentrations. Because only 10% can penetrate into body cells, it is ineffective against intracellular tuberculosis bacteria and can only kill extracellular tuberculosis bacteria. It has a stronger bactericidal effect on bacteria in the reproductive period than on bacteria in the resting period. Unlike penicillin, its bactericidal rate is proportional to the drug concentration. Its antibacterial effect is strongest at a pH value of 7.8, and its effect is greatly weakened when the pH value drops below 6.

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