HARRINGTONINE CAS#26833-85-2

CAS Number: 26833-85-2
Chemical Formula: C28H37NO9
Synonyms:

HARRINGTONIN
HARRINGTONINE
2'R-HARRINGTONINE

Appearance: White Powder

MOQ (Minimum Order Quantity): 1 FCL (Full Container Load)

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Product Details

HARRINGTONINE CAS#26833-85-2

Harringtonine is a natural alkaloid that inhibits protein synthesis at low micromolar concentrations. It immobilizes ribosomes immediately after the initiation of translation. While harringtonine has drawn some interest in mitigating cancer, its homolog homoharrington is more effective, particularly for chronic myelogenous leukemia. The ability of harringtonine to immobilize initiating ribosomes can be used to capture ribosome-protected mRNA fragments for evaluating translation.

HARRINGTONINE Chemical Properties

Melting point	73～75℃
Boiling point	679.4±55.0 °C(Predicted)
density	1.35±0.1 g/cm3(Predicted)
storage temp.	2-8°C
solubility	DMF: 25 mg/ml; DMSO: 25 mg/ml; Ethanol: 25 mg/ml; Ethanol:PBS(pH 7.2) (1:1): 0.5 mg/ml
pka	11.62±0.29(Predicted)
form	A crystalline solid
color	White to light yellow