Ceftriaxone sodium CAS#104376-79-6

CAS Number: 104376-79-6

Chemical Formula: C18H21N8NaO8S3

Synonyms:

Ceftriaxone SodiuM Trihydrate

Ceftriaxone sodiuM sesquaterhydrate

(6R,7R)-7-[[(2Z)-2-(2-AMino-4-thiazolyl)-2-(MethoxyiMino)acetyl]aMino]-8-oxo-3-[[(1,2,5,6-tetrahydro-2-Methyl-Chemicalbook5,6-dioxo-1,2,4-triazin-3-yl)thio]Methyl]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylicAcidSodiuMSaltHydrate

Appearance: White solid

HS Code:29349990

MOQ (Minimum Order Quantity): 1 FCL (Full Container Load)

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Product Details

Products Description of Ceftriaxone sodium CAS#104376-79-6

Ceftriaxone is a third-generation, broad-spectrum cephalosporin antibiotic that disrupts the synthesis of the peptidoglycan layer of bacterial cell walls. It has been shown to increase excitatory amino acid transporter-2 pump expression in the central nervous system and to reduce glutamatergic toxicity in both in vitro and in vivo models.

Parameters

Melting point	236 °C
alpha	D25 -165° (c = 1 in water) (calc for water-free substance)
refractive index	-160 ° (C=1, H2O)
storage temp.	Keep in dark place,Inert atmosphere,2-8°C
solubility	H2O: soluble50mg/mL
pka	~3 (COOH), 3.2 (NH3+), 4.1 (enolic OH)
form	powder or crystals
color	White to Off-White
Water Solubility	Freely soluble in water
InChIKey	FDRNWTJTHBSPMW-BBJOQENWSA-L
Safety Information
Hazard Codes	Xn
Risk Statements	36/37/38-42/43
Safety Statements	26-36-45-37-24-22
WGK Germany	1
RTECS	XI0368800
HS Code	29349990
Toxicity	LD50 in male, female, mice, rats (mg/kg): 3000, 2800, 2175, 2175 i.v.; >10000 all species orally; >5000 all species s.c. (Teelman)
MSDS Information
Provider	Language
SigmaAldrich	English

Ceftriaxone sodium Usage And Synthesis
Description	Ceftriaxone is a third-generation, broad-spectrum cephalosporin antibiotic that disrupts the synthesis of the peptidoglycan layer of bacterial cell walls. It has been shown to increase excitatory amino acid transporter-2 pump expression in the central nervous system and to reduce glutamatergic toxicity in both in vitro and in vivo models.
Chemical Properties	White Crystalline Solid
Uses	antipsychotic
Uses	A potentially useful antibacterial agent for proteomics research.
Uses	An antibacterial, a third-generation cephalosporin.
Definition	ChEBI: Ceftriaxone disodium salt hemiheptahydrate is a cephalosporin.
Brand name	Rocephin (Roche).
Biological Activity	β -lactam antibiotic. Displays neuroprotective activity in vivo via upregulation and increased activity of the EAAT2 glutamate transporter.

Product Application of Ceftriaxone sodium CAS#104376-79-6

Ceftriaxone sodium (CAS#104376-79-6) belongs to the third-generation cephalosporin antibiotics. It killing micro organism through inhibiting the synthesis of bacterial mobilephone walls. It has a extensive antibacterial spectrum and excessive stability, and is appropriate for treating touchy bacterial infections in more than one components such as the respiratory system, urinary system, stomach cavity, and pelvic cavity

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