N-TERT-BUTYL-ALPHA-PHENYLNITRONE CAS#3376-24-7
CAS Number: 3376-24-7
Chemical Formula:C11H15NO
Synonyms:
PBN
PHENYL N-TERT-BUTYLNITRONE;
n-tert-butyl-2-phenylnitrone
MOQ (Minimum Order Quantity): 1 FCL (Full Container Load)
Appearance: White Powder
N-TERT-BUTYL-ALPHA-PHENYLNITRONE CAS#3376-24-7
Most commonly-used free radical trap. An antioxidant that has been shown to act as a protective agent in several experimental models of neurodegenerative disorders. Inhibits lipid peroxidation in rat liver microsomes. Also prevents the induction of inducible nitric oxide synthase (iNOS) by reactive oxygen species.
| N-TERT-BUTYL-ALPHA-PHENYLNITRONE Chemical Properties |
| Melting point | 73-74 °C(lit.) |
| Boiling point | 283℃ |
| density | 0.990 |
| refractive index | 1.5480 (estimate) |
| Fp | 119℃ |
| storage temp. | Store at <= 20°C. |
| solubility | DMSO: soluble |
| pka | 1.50±0.53(Predicted) |
| form | powder |
| color | white |
| Water Solubility | Soluble in DMSO (10 mg/ml), chloroform (50 mg/ml), and water (20 mg/ml). |
| Merck | 14,7056 |
| BRN | 2044028 |
| CAS DataBase Reference | 3376-24-7(CAS DataBase Reference) |
| EPA Substance Registry System | 2-Propanamine, 2-methyl-N-(phenylmethylene)-, N-oxide (3376-24-7) |
| Safety Statements | 22-24/25 |
| WGK Germany | 3 |
| RTECS | TX1760000 |
| F | 10 |
| TSCA | Yes |
| HS Code | 2929 90 00 |
| Safety Information |
Product Application of N-TERT-BUTYL-ALPHA-PHENYLNITRONE CAS#3376-24-7
N-tert-Butyl-a-phenylnitrone is a commonly-used free radical trap. It contains radical scavenging activity and an ability to inhibit Cox-2 (cyclooxygenase-2). N-tert-Butyl-a-phenylnitrone is an antioxidant that has been shown to act as a protective agent in several experimental models of neurodegenerative disorders. N-tert-Butyl-a-phenylnitrone inhibits lipid peroxidation in rat liver microsomes. It also prevents the induction of inducible nitric oxide synthase (iNOS) by reactive oxygen species.
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