N-TERT-BUTYL-ALPHA-PHENYLNITRONE CAS#3376-24-7

  • CAS Number: 3376-24-7

  • Chemical Formula:C11H15NO

  • Synonyms:

    • PBN

    • PHENYL N-TERT-BUTYLNITRONE;

    • n-tert-butyl-2-phenylnitrone

    Appearance:  White Powder

  • MOQ (Minimum Order Quantity): 1 FCL (Full Container Load)



Product Details

N-TERT-BUTYL-ALPHA-PHENYLNITRONE CAS#3376-24-7

Most commonly-used free radical trap. An antioxidant that has been shown to act as a protective agent in several experimental models of neurodegenerative disorders. Inhibits lipid peroxidation in rat liver microsomes. Also prevents the induction of inducible nitric oxide synthase (iNOS) by reactive oxygen species.


N-TERT-BUTYL-ALPHA-PHENYLNITRONE Chemical Properties
Melting point 73-74 °C(lit.)
Boiling point 283℃
density 0.990
refractive index 1.5480 (estimate)
Fp 119℃
storage temp. Store at <= 20°C.
solubility DMSO: soluble
pka1.50±0.53(Predicted)
form powder
color white
Water Solubility Soluble in DMSO (10 mg/ml), chloroform (50 mg/ml), and water (20 mg/ml).
Merck 14,7056
BRN 2044028
CAS DataBase Reference3376-24-7(CAS DataBase Reference)
EPA Substance Registry System2-Propanamine, 2-methyl-N-(phenylmethylene)-, N-oxide (3376-24-7)

Safety Statements 22-24/25
WGK Germany 3
RTECS TX1760000
10
TSCA Yes
HS Code 2929 90 00


Safety Information

Product Application of  N-TERT-BUTYL-ALPHA-PHENYLNITRONE CAS#3376-24-7

N-tert-Butyl-a-phenylnitrone is a commonly-used free radical trap. It contains radical scavenging activity and an ability to inhibit Cox-2 (cyclooxygenase-2). N-tert-Butyl-a-phenylnitrone is an antioxidant that has been shown to act as a protective agent in several experimental models of neurodegenerative disorders. N-tert-Butyl-a-phenylnitrone inhibits lipid peroxidation in rat liver microsomes. It also prevents the induction of inducible nitric oxide synthase (iNOS) by reactive oxygen species.


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