N-Methylformamide CAS#123-39-7

CAS Number: 123-39-7
Chemical Formula: C2H5NO
Synonyms:

N-MENTHYL FORMAMID
Formamide,N-methyl-
Formylmethylamine

Appearance: Transperant Liquid

MOQ (Minimum Order Quantity): 1 FCL (Full Container Load)

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Product Details

N-Methylformamide CAS#123-39-7

N-methylformamide is a clear colorless liquid with a slight amine odor. It is a water-soluble organic solvent. As an adjuvant antineoplastic agent, N-methylformamide depletes cellular glutathione, a key molecule involved in the antioxidation of reactive oxygen species (ROS) and other free radicals, thereby enhancing ionizing radiation-induced DNA cross-linking in and terminal differentiation of tumor cells. (NCI04)

N-Methylformamide Chemical Properties

Melting point	-4 °C (lit.)
Boiling point	198-199 °C (lit.)
density	1.011 g/mL at 25 °C (lit.)
vapor pressure	20Pa at 20℃
refractive index	n20/D 1.432(lit.)
Fp	>230 °F
storage temp.	Sealed in dry,Room Temperature
solubility	soluble in water, chloroform, alcohols, acetone, ethylacetate but not in diethyl ether and petroleum ether
pka	16.48±0.23(Predicted)
form	Liquid
color	Clear colorless
Odor	strong odor
Relative polarity	6.2
Water Solubility	miscible
Merck	14,6076
BRN	1098352
Dielectric constant	171.0
Exposure limits	ACGIH: TWA 1 ppm (Skin)
InChI	1S/C2H5NO/c1-3-2-4/h2H,1H3,(H,3,4)
InChIKey	ATHHXGZTWNVVOU-UHFFFAOYSA-N
SMILES	[H]C(=O)NC
LogP	-0.97
CAS DataBase Reference	123-39-7(CAS DataBase Reference)
NIST Chemistry Reference	Formamide, N-methyl-(123-39-7)
EPA Substance Registry System	N-Methylformamide (123-39-7)

Safety Information

Hazard Codes	T
Risk Statements	61-21-R61-R21
Safety Statements	53-45-S53-S45
WGK Germany	1
RTECS	LQ3000000
TSCA	TSCA listed
PackingGroup	II
HS Code	29241990
Storage Class	6.1C - Combustible acute toxic Cat.3 toxic compounds or compounds which causing chronic effects
Hazard Classifications	Acute Tox. 4 Dermal Repr. 1B
Hazardous Substances Data	123-39-7(Hazardous Substances Data)
Toxicity	LD50 in mice (mg/kg): 2300 i.p.; 2600 orally; 1580 i.v.; 2700 i.m. (Langdon)

Product Application of N-Methylformamide CAS#123-39-7

N-Methylformamide is used to prepare methyl isocyanate. It is used as an extraction solvent for aromatic hydrocarbons and acts as a ligand in coordination chemistry. It is employed as a solvent in oil refineries and in aluminum electrolytic capacitors. Further, it is used as a reagent in organic synthesis. In addition to this, it is used as an investigational anticancer drug and an intermediate in the production of some pharmaceutical compounds.

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