Glyceryl monostearate CAS#31566-31-1

CAS Number: 31566-31-1
Chemical Formula: C21H42O4
Synonyms:

abracols.l.g.
admul
Glycerol Monosterate 35% GMS 401 SE

Appearance: White Powder

MOQ (Minimum Order Quantity): 1 FCL (Full Container Load)

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Product Details

Glyceryl monostearate CAS#31566-31-1

§184.1324(a) Glyceryl monostearate, also known as monostearin, is a mixture of variable proportions of glyceryl monostearate (C21H42O4), and glyceryl esters of fatty acids present in commercial stearic acid. Glyceryl monostearate is prepared by glycerolysis of certain fats or oils that are derived from edible sources or by esterification, with glycerin, of stearic acid that is derived from edible sources.

Glyceryl monostearate Chemical Properties

Melting point	78-81 °C
Boiling point	410.96°C (rough estimate)
density	0.9700
refractive index	1.4400 (estimate)
Fp	>500
storage temp.	Sealed in dry,Store in freezer, under -20°C
solubility	Soluble in hot ethanol, ether, chloroform, hot acetone, mineral oil, and fixed oils. Practically insoluble in water, but may be dispersed in water with the aid of a small amount of soap or other surfactant.
form	Powder
color	Pure-white or cream-colored, wax-like solid
Odor	faint odor
Water Solubility	Soluble in hot organic solvents.Soluble in hot water. Slightly soluble in ethanol. Insoluble in aliphatic solvents.
Merck	14,4489
Exposure limits	ACGIH: TWA 10 mg/m3; TWA 3 mg/m3
Cosmetics Ingredients Functions	SKIN CONDITIONING - EMOLLIENT SURFACTANT - EMULSIFYING
InChI	InChI=1S/C21H42O4/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-21(24)25-19-20(23)18-22/h20,22-23H,2-19H2,1H3
InChIKey	VBICKXHEKHSIBG-UHFFFAOYSA-N
SMILES	C(OCC(CO)O)(=O)CCCCCCCCCCCCCCCCC
CAS DataBase Reference	31566-31-1(CAS DataBase Reference)
EPA Substance Registry System	Glyceryl monostearate (31566-31-1)

Safety Information

WGK Germany	1
TSCA	TSCA listed
HS Code	2918199890
Toxicity	LD50 ipr-mus: 200 mg/kg NTIS** AD277-689

Product Application Of Glyceryl monostearate CAS#31566-31-1

The many varieties of glyceryl monostearate are used as nonionic emulsifiers, stabilizers, emollients, and plasticizers in a variety of food, pharmaceutical, and cosmetic applications. It acts as an effective stabilizer, that is, as a mutual solvent for polar and nonpolar compounds that may form water-in-oil or oil-in-water emulsions.These properties also make it useful as a dispersing agent for pigments in oils or solids in fats, or as a solvent for phospholipids, such as lecithin.
Glyceryl monostearate has also been used in a novel fluidized hot-melt granulation technique for the production of granules and tablets.
Glyceryl monostearate is a lubricant for tablet manufacturing and may be used to form sustained-release matrices for solid dosage forms. Sustained-release applications include the formulation of pellets for tablets or suppositories, and the preparation of a veterinary bolus. Glyceryl monostearate has also been used as a matrix ingredient for a biodegradable, implantable, controlledrelease dosage form.
When using glyceryl monostearate in a formulation, the possibility of polymorph formation should be considered. The aform is dispersible and foamy, useful as an emulsifying agent or preservative. The denser, more stable, b-form is suitable for wax matrices. This application has been used to mask the flavor of clarithromycin in a pediatric formulation.

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