Colorless crystalline powder. Melting point is 238-240 ℃ (decomposition). Can be dissolved in hot water, hot alcohol and dilute sodium hydroxide solution, slightly soluble in water and alcohol, almost insoluble in ether and chloroform. Odorless, tasteless. In dry air is stable, prolonged boiling in the water. or strong base will be destroyed. pH of saturated aqueous solution is 5.5.
Allantoin Chemical Properties |
Melting point | 230 °C (dec.) (lit.) |
Boiling point | 283.17°C (rough estimate) |
density | 1.6031 (rough estimate) |
refractive index | 1.8500 (estimate) |
Fp | 230-234°C |
storage temp. | 2-8°C |
solubility | H2O: soluble0.1g/10 mL, clear, colorless |
pka | 8.96(at 25℃) |
form | Powder |
color | White |
Odor | odorless, tasteless |
Water Solubility | Slightly soluble in water. Freely soluble in alkalis |
Decomposition | 230-234 ºC |
Merck | 14,258 |
BRN | 102364 |
Stability: | Stable. Incompatible with strong oxidizing agents. |
Cosmetics Ingredients Functions | SOOTHING |
Cosmetic Ingredient Review (CIR) | Allantoin (97-59-6) |
InChI | 1S/C4H6N4O3/c5-3(10)6-1-2(9)8-4(11)7-1/h1H,(H3,5,6,10)(H2,7,8,9,11) |
InChIKey | POJWUDADGALRAB-UHFFFAOYSA-N |
SMILES | NC(=O)NC1NC(=O)NC1=O |
LogP | -2.26 at 20℃ |
CAS DataBase Reference | 97-59-6(CAS DataBase Reference) |
NIST Chemistry Reference | Urea, (2,5-dioxo-4-imidazolidinyl)-(97-59-6) |
EPA Substance Registry System | Allantoin (97-59-6) |
Safety Information |
Hazard Codes | Xn,Xi |
Risk Statements | 22-36/37/38 |
Safety Statements | 22-24/25-36-26 |
WGK Germany | 1 |
RTECS | YT1600000 |
TSCA | TSCA listed |
HS Code | 29332100 |
Storage Class | 11 - Combustible Solids |
Hazardous Substances Data | 97-59-6(Hazardous Substances Data) |
Product Application of Allantoin CAS#97-59-6
allantoin is a botanical extract said to be healing, calming, and soothing, it can also help protect the skin from harmful external factors (e.g., wind burn). It is considered an excellent temporary anti-irritant and is believed to stimulate new tissue growth, helping heal damaged skin. Allantoin is appropriate for sensitive, irritated, and acne skins. Derived from the comfrey root, it is considered non-allergenic.
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