Pancreatin CAS#8049-47-6
CAS Number: 8049-47-6
Chemical Formula: N/A
Synonyms:
beefviokase
diastasevera
PANCREATIN 4X USP GRANULAR
MOQ (Minimum Order Quantity): 1 FCL (Full Container Load)
Appearance: White Powder
Pancreatin CAS#8049-47-6
Pancreatin (Panteric) is a substance obtained from the fresh pancreas of the hog or the ox and contains a mixture of enzymes, principally pancreatic amylase (amylopsin), protease, and pancreatic lipase (steapsin). It converts not less than 25 times its weight of USP Potato Starch Reference Standard into soluble carbohydrates and not less than 25 times its weight of casein into proteoses. It acts best in neutral or faintly alkaline media, and excessive acid or alkali renders it inert. Pancreatin can be prepared by extracting the fresh gland with 25% alcohol or with water and subsequently precipitating with alcohol. Besides the enzymes mentioned, it contains some trypsinogen, which can be activated by intestinal enterokinase; chymotrypsinogen, which is converted by trypsin to chymotrypsin; and carboxypeptidase.
Pancreatin is used largely for predigestion of food and for the preparation of hydrolysates. The value of its enzymes orally must be very small because they are digested by pepsin and acid in the stomach, although some of them may escape into the intestines without change. Even if they are protected by enteric coatings, it is doubtful they could be of great assistance in digestion.
Pancreatin Chemical Properties |
bulk density | 400kg/m3 |
density | 1.4-1.52 |
vapor pressure | 0Pa at 25℃ |
storage temp. | -20°C |
solubility | Soluble or partly soluble in water forming a slightly turbid solution; practically insoluble in ethanol (96%) and in ether . |
form | powder |
color | beige |
PH | 5-6 (20°C, 10g/L in H2O) |
biological source | Porcine pancreas |
Water Solubility | Soluble in water. Insoluble in alcohol and ether. |
Merck | 13,7075 |
Specific Activity | 8× USP specifications |
Stability: | Stable. Incompatible with alcohols, strong acids. |
Cosmetics Ingredients Functions | HAIR CONDITIONING |
LogP | -1.3 at 20℃ and pH5.7-5.8 |
EPA Substance Registry System | Pancreatin (8049-47-6) |
Safety Information |
Hazard Codes | Xn |
Risk Statements | 36/37/38-42-42/43 |
Safety Statements | 22-24-26-36/37-37/39 |
WGK Germany | 1 |
RTECS | RT9033000 |
F | 3-10 |
Autoignition Temperature | >360°C |
TSCA | TSCA listed |
HS Code | 35079090 |
Storage Class | 13 - Non Combustible Solids |
Hazard Classifications | Eye Irrit. 2 |
Hazardous Substances Data | 8049-47-6(Hazardous Substances Data) |
Toxicity | LD50 orl-rat: >10 g/kg YACHDS 3,2427,75 |
Product Application Of Pancreatin CAS#8049-47-6
Hydrolyzes starch into dextrins and sugar Pancreatin from porcine pancreas is used in the treatment of steatorrhea by lipase supplementation therapy and for pancreatic diabetes. It is also used in the removal of formalin-fixed tissues from arterial grafts without causing damage in fiber integrity. Further, it finds uses in contact lenses. In addition to this, it hydrolyzes starch into dextrins and sugar. It is also used to treat conditions responsible for deficiency in pancreatic secretions, such as surgical pancreatectomy, pancreatitis and cystic fibrosis.
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