Sodium carboxymethyl cellulose CAS#9004-32-4
CAS Number: 9004-32-4
Chemical Formula: C6H7O2(OH)2CH2COONa
Synonyms:
Aquacide I, Calbiochem
Aquacide II, Calbiochem
SODIUM CARBOXY METHYL CELLULOSE (CMC)
MOQ (Minimum Order Quantity): 1 FCL (Full Container Load)
Appearance: White Powder
Sodium carboxymethyl cellulose CAS#9004-32-4
Sodium carboxymethyl cellulose(9004-32-4) is a water-soluble polymer. As a solution in water, it has thixotropic properties. It is useful in helping to hold the components of pyrotechnic compositions in aqucous suspension (e.g., in the making of black match). It is also an especially effective binder that can be used in small amounts in compositions, where the binder can intcrfere with the intended effect (e.g., in strobe compositions). However, its sodium content obviously precludes its use in most color compositions. Sodium carboxymethyl-cellulose is manufactured from cellulose by various proccsses that replacc some of the hy drogen atoms in the hydroxyl[OH] groups of the cellulose molecule with acidic carboxymethyl [-CH2CO.OH] groups,which are neutralized to form the corresponding sodium salt. Sodium carboxymethyl cellulose is white when pure; industrial grade material may be grayish-white or cream granules or powder. |
Sodium carboxymethyl cellulose Chemical Properties |
Melting point | 274 °C (dec.) |
density | 1,6 g/cm3 |
refractive index | 1.515 |
FEMA | 2239 | CARBOXYMETHYLCELLULOSE |
storage temp. | room temp |
solubility | H2O: 20 mg/mL, soluble |
pka | 4.30(at 25℃) |
form | low viscosity |
color | White to light yellow |
Odor | Odorless |
PH | pH (10g/l, 25℃) 6.0~8.0 |
PH Range | 6.5 - 8.5 |
biological source | wood (pulp) |
Water Solubility | soluble |
Merck | 14,1829 |
Stability: | Stable. Incompatible with strong oxidizing agents. |
Cosmetics Ingredients Functions | EMULSION STABILISING |
Cosmetic Ingredient Review (CIR) | Sodium carboxymethyl cellulose (9004-32-4) |
InChI | 1S/C6H12O6.C2H4O2.Na/c7-1-3(9)5(11)6(12)4(10)2-8;1-2(3)4;/h1,3-6,8-12H,2H2;1H3,(H,3,4); |
InChIKey | DPXJVFZANSGRMM-UHFFFAOYSA-N |
SMILES | [Na].OC(C(O)C(O)C=O)C(O)CO.OC(=O)C |
EPA Substance Registry System | Sodium carboxymethyl cellulose (9004-32-4) |
Safety Information |
Risk Statements | 40 |
Safety Statements | 24/25 |
WGK Germany | 1 |
RTECS | FJ5950000 |
F | 3 |
Autoignition Temperature | 698 °F |
TSCA | TSCA listed |
HS Code | 39123100 |
Storage Class | 11 - Combustible Solids |
Toxicity | LD50 oral in rabbit: > 27gm/kg |
Product Application Of Sodium carboxymethyl cellulose CAS#9004-32-4
Sodium carboxymethyl cellulose (NaCMC) is the sodium salt of carboxymethyl cellulose, an anionic derivative.It is widely used in oral and topical pharmaceutical formulations, primarily for its viscosity-increasing properties. Viscous aqueous solutions are used to suspend powders intended for either topical application or oral and parenteral administration. Carboxymethylcellulose sodium may also be used as a tablet binder and disintegrant, and to stabilize emulsions.
Higher concentrations, usually 3–6%, of the medium-viscosity grade are used to produce gels that can be used as the base for applications and pastes; glycols are often included in such gels to prevent them drying out. Carboxymethylcellulose sodium is also used in self-adhesive ostomy, wound care, and dermatological patches as a muco-adhesive and to absorb wound exudate or transepidermal water and sweat. This muco-adhesive property is used in products designed to prevent post-surgical tissue adhesions; and to localize and modify the release kinetics of active ingredients applied to mucous membranes; and for bone repair. Encapsulation with carboxymethylcellulose sodium can affect drug protection and delivery. There have also been reports of its use as a cyto-protective agent.
Carboxymethylcellulose sodium is also used in cosmetics, toiletries, surgical prosthetics, and incontinence, personal hygiene, and food products.
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