2,3-Difluorophenol CASZ#6418-38-8
CAS Number: 6418-38-8
Chemical Formula: C6H4F2O
Synonyms:
2,3-DIFLUOROPHENOL
PHENOL, 2,3-DIFLUORO-
2,3-Difluorophenol ,99%
MOQ (Minimum Order Quantity): 1 FCL (Full Container Load)
Appearance: White Powder
2,3-Difluorophenol CASZ#6418-38-8
In a 500 mL round-bottomed flask, dissolve 2,3-difluorophenylboronic acid (30 g, 189.98 mmol, 1.00 eq.) in dichloromethane (250 mL). Hydrogen peroxide (30 mL) was added slowly and dropwise under stirring conditions. The reaction mixture was stirred continuously at 25°C for 2 hours. Upon completion of the reaction, the reaction mixture was washed sequentially with water and saturated saline, the organic phase was dried over anhydrous magnesium sulfate, and subsequently concentrated under reduced pressure to afford 2,3-difluorophenol 23 g (93% yield) as a brown oil.
2,3-Difluorophenol Chemical Properties |
Melting point | 39-42 °C (lit.) |
Boiling point | 54 °C/25 mmHg (lit.) |
density | 1.2483 (estimate) |
Fp | 134 °F |
storage temp. | Inert atmosphere,2-8°C |
pka | 7.71±0.10(Predicted) |
form | powder to lump to clear liquid |
color | White or Colorless to Almost white or Almost colorless |
BRN | 2082265 |
InChI | InChI=1S/C6H4F2O/c7-4-2-1-3-5(9)6(4)8/h1-3,9H |
InChIKey | RPEPGIOVXBBUMJ-UHFFFAOYSA-N |
SMILES | C1(O)=CC=CC(F)=C1F |
CAS DataBase Reference | 6418-38-8(CAS DataBase Reference) |
Safety Information |
Hazard Codes | F,Xn,Xi,C |
Risk Statements | 11-22-36/37/38-34-20/21/22 |
Safety Statements | 26-45-36/37/39-16 |
RIDADR | UN 1325 4.1/PG 2 |
WGK Germany | 3 |
Hazard Note | Irritant |
HazardClass | 4.1 |
PackingGroup | III |
HS Code | 29081000 |
Storage Class | 3 - Flammable liquids |
Hazard Classifications | Acute Tox. 4 Oral |
Product Application Of 2,3-Difluorophenol CASZ#6418-38-8
2,3-Difluorophenol was used in the synthesis of material-poly{methyl[3-(2-hydroxy-3,4-difluoro)phenyl]propyl siloxane} (PMDFPS) sensitive to toxic organophosphate. |
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