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Loratadine CAS#79794-75-5
CAS Number: 79794-75-5
Chemical Formula: C22H23ClN2O2
Synonyms:
LORATADINE
CLARATYNE
LORATADINE-D5
Appearance: White powder
HS Code:29333990
MOQ (Minimum Order Quantity): 1 FCL (Full Container Load)
Products Description of Loratadine CAS#79794-75-5
Loratadine is a commonly used antiallergic drug. It belongs to the second generation of long-acting tricyclic antihistamines. It has a fast onset of action, strong effects, and does not contain hormones. After absorption by the human body, it is metabolized into more active desloratadine. It inhibits the allergic symptoms caused by histamine by competitively inhibiting histamine H1 receptors. It has no obvious anticholinergic and central inhibitory effects. It is clinically used to relieve symptoms related to allergic rhinitis, such as sneezing, runny nose and nasal itching, as well as itching and burning sensation in the eyes. It is also used to relieve the symptoms of chronic urticaria and other allergic skin diseases. Toxicology: Animal tests have no mutagenic or teratogenic effects.
Parameters
| Melting point | 134-136°C |
| Boiling point | 531.3±50.0 °C(Predicted) |
| density | 1.261±0.06 g/cm3(Predicted) |
| RTECS | TM6129200 |
| storage temp. | 2-8°C |
| solubility | DMSO: 26 mg/mL, soluble |
| form | powder |
| pka | 4.27±0.20(Predicted) |
| color | white |
| Water Solubility | It is soluble in DMSO (50 mg/ml), ethanol (77 mg/ml at 25°C), water (<1 mg/ml at 25°C), chloroform, and methanol. |
| Merck | 145578 |
| BCS Class | 2 |
| Stability: | Stable, but may be heat sensitive - refrigerate. Incompatible with strong oxidizing agents. |
| InChIKey | JCCNYMKQOSZNPW-UHFFFAOYSA-N |
| CAS DataBase Reference | 79794-75-5(CAS DataBase Reference) |
| EPA Substance Registry System | 1-Piperidinecarboxylic acid, 4-(8-chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-, ethyl ester (79794-75-5) |
| Safety Information | |
| Hazard Codes | Xi |
| Risk Statements | 36/37/38 |
| Safety Statements | 22-24/25-36-26 |
| RIDADR | 3077 |
| WGK Germany | 2 |
| HS Code | 29333990 |
| Hazardous Substances Data | 79794-75-5(Hazardous Substances Data) |
Product Application of Loratadine CAS#79794-75-5
Antihistamines are highly selective for peripheral nerve H1 receptors, with strong and long-lasting effects. They are used for allergic arthritis and allergic rhinitis.
National Class II antiallergic new drug, used to relieve nasal and non-nasal symptoms of seasonal allergic rhinitis and relieve chronic urticaria
Factory and Equipment Show
Fast delivery time
Inventory 2-3 working days New production 7-10 working days
