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Gentamicin sulfate CAS#1405-41-0
CAS Number: 1405-41-0
Chemical Formula: C60H127N15O26S
Synonyms:
GENTAMICIN 2,5-SULFATE HYDRATE
Gentamicin Sulfate
Gentamicin sulfate solution
Appearance: Light yellow powder
HS Code:29419010
MOQ (Minimum Order Quantity): 1 FCL (Full Container Load)
Products Description of Gentamicin sulfate CAS#1405-41-0
Gentamycin sulfate is a glycoside bactericidal antibiotic composed of amino sugars and ligands. It is the sulfate of gentamicin and has an antibacterial spectrum similar to that of kanamycin. It is mainly used for systemic or local infections caused by Gram-negative bacteria such as Escherichia coli, Shigella dysenteriae, Klebsiella pneumoniae, Proteus, Chemicalbook Pseudomonas aeruginosa, etc. It is used in ophthalmology for conjunctivitis, keratitis, etc. It can be taken orally for intestinal infections or preparation before colon surgery; it can also be used in combination with metronidazole or clindamycin to reduce the infection rate of colon surgery.
Parameters
| Melting point | 218-237°C |
| alpha | D25 +102° |
| density | 1.000 g/cm3 |
| storage temp. | 2-8°C |
| solubility | H2O: 50 mg/mL As stock solution, store at −20°C. Stable at 37°C for 5 days. |
| form | powder |
| color | colorless to light yellow |
| Odor | odorless |
| PH | 4.0-5.5 (0.1g/mL in H2O) |
| optical activity | [α]20/D +110±8°, c = 1% in H2O |
| biological source | Micromonospora purpurea |
| Water Solubility | Soluble in water |
| Merck | 134403 |
| InChIKey | RDEIXVOBVLKYNT-HDZPSJEVSA-N |
| CAS DataBase Reference | 1405-41-0(CAS DataBase Reference) |
| EPA Substance Registry System | Gentamicin sulfate (1405-41-0) |
| Safety Information | |
| Hazard Codes | Xn |
| Risk Statements | 42/43 |
| Safety Statements | 23-36/37-45-22-24/25 |
| WGK Germany | 2 |
| RTECS | LY2625000 |
| F | 3 |
| HS Code | 29419010 |
| Toxicity | LD50 in mice (mg base/kg): 430 i.p.; 485 s.c.; 75 i.v.; >9050 orally (Black) |
Product Application of Gentamicin sulfate CAS#1405-41-0
Clinically used for sepsis, respiratory tract infection, biliary tract infection, purulent peritonitis, intracranial infection, urinary tract infection and bacillary dysentery caused by Staphylococcus aureus, Pseudomonas aeruginosa, Escherichia coli, Shigella dysenteriae, Klebsiella, Proteus and other sensitive bacteria.
Gentamicin binds to the 30S ribosomal subunit to cause code reading errors, blocking the transfer of peptidyl-tRNA from the receptor site to the donor site. The bactericidal effect of gentamicin on Pseudomonas Chemicalbook is to bind to the outer membrane part of the cell membrane, replace the original cations, make the membrane unstable, and form holes on the cell surface. Antibacterial spectrum: Gram-negative bacteria, Staphylococcus and other Gram-positive bacteria.
Used to treat sepsis, urinary tract infection, Staphylococcus infection, endocarditis and other diseases
Factory and Equipment Show
Fast delivery time
Inventory 2-3 working days New production 7-10 working days
