< >

Metronidazole CAS#443-48-1

CAS Number:443-48-1

Chemical Formula: C6H9N3O3

Synonyms:

TIMTEC-BB SBB001486

1-(2-Hydroxy-1-ethyl)-2-methyl-5-nitroimidazole

1-(2-hydroxyethyl)-2-methyl-5-nitroimidazole

Appearance: White crystal

HS Code:29332990

MOQ (Minimum Order Quantity): 1 FCL (Full Container Load)

Contact Now E-Mail Telephone WhatsApp

Product Details

Products Description of Metronidazole CAS#443-48-1

Metronidazole is a nitroimidazole antibiotic, also known as metronidazole, metronidazole, metronidazole, and metronidazole. It has a killing effect on anaerobic microorganisms. The metabolites generated when it is reduced in the human body also have anti-anaerobic effects, inhibiting the synthesis of bacterial deoxyribonucleic acid, thereby interfering with the growth and reproduction of bacteria, and eventually causing bacterial death. Anti-anaerobic bacteria generally include: Bacteroides fragilis, Fusobacterium (named because the two ends of the bacterial body are sharp and fusiform), Clostridium tetani, Peptococcus, Peptostreptococcus, and Giardia. It was originally used to treat vaginal trichomoniasis, and the clinical effect was very significant. Later, people found that metronidazole can also kill anaerobic bacteria that cause oral infections. In 1978, it was identified by the World Health Organization as a specific drug for anti-anaerobic infections and is widely used in the prevention and treatment of oral anaerobic infections. In hospitals, this product is also often used to prevent and treat respiratory tract, digestive tract, abdominal and pelvic infections, skin, soft tissue and bone and joint infections, pericarditis, sepsis and brain treatment caused by anaerobic bacteria.

Parameters

Melting point	159-161 °C (lit.)
Boiling point	301.12°C (rough estimate)
density	1.3994 (rough estimate)
refractive index	1.5800 (estimate)
Fp	9℃
storage temp.	2-8°C
solubility	acetic acid: 0.1 M, clear, faintly yellow
form	crystalline
pka	pKa 2.62(H2O,t =25±0.2,Iundefined) (Uncertain)
color	white to light yellow
Water Solubility	<0.1 g/100 mL at 20 ºC
Merck	146157
BRN	611683
BCS Class	1,3
Stability:	Stable. Incompatible with strong oxidizing agents.
InChIKey	VAOCPAMSLUNLGC-UHFFFAOYSA-N
LogP	-0.02
IARC	2B (Vol. 13, Sup 7) 1987
NIST Chemistry Reference	Metronidazole(443-48-1)
EPA Substance Registry System	Metronidazole (443-48-1)
Safety Information
Hazard Codes	Xn
Risk Statements	40-46-45-39/23/24/25-23/24/25-11
Safety Statements	36/37-45-53-16-7
WGK Germany	3
RTECS	NI5600000
F	8
HS Code	29332990
Hazardous Substances Data	443-48-1(Hazardous Substances Data)

Product Application of Metronidazole CAS#443-48-1

This product has been used to treat vaginal trichomoniasis since 1959 and intestinal and exo-amoebiasis since 1970. It has high efficacy, low toxicity and wide application. It has mutagenic and teratogenic effects in animal experiments.

It has strong antibacterial effects on most anaerobic bacteria

It is used to treat amoebiasis, trichomoniasis and anaerobic infections

Factory and Equipment Show