Polyvinylpyrrolidone CAS#9003-39-8

CAS Number: 9003-39-8
Chemical Formula: CH4
Synonyms:

toxobin
vinylpyrrolidinonepolymer
K 30 POVIDONE K 30 BP/USP

Appearance: White Powder

MOQ (Minimum Order Quantity): 1 FCL (Full Container Load)

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Product Details

Polyvinylpyrrolidone CAS#9003-39-8

Polyvinylpyrrolidone is abbreviated as PVP, and is the polymer of vinylpyrrolidone. According to the different degree of polymerization, it is further classified into soluble PVP and insoluble PVPP (polyvinyl polypyrrolidone). Molecular weight of the soluble PVP is 8,000 to 10,000.The soluble PVP can be used as a precipitating agent which can be settle down through its action with polyphenols. Using this method, it is easily to have residual PVP in the alcohol. Due to the savings effect of PVP inside the human body, the World Health Organization doesn’t recommend to apply this substance. In recent years, the use of soluble PVP has been rare. Insoluble PVPP system had began to be used in the beer industry since the early 1960s. It has a relative molecule weight greater than the relative mass greater than 700,000. It is a insoluble polymer derived from the further cross-linking and polymerization of PVP and can be used as an adsorbent of polyphenols with a good efficacy.

Polyvinylpyrrolidone Chemical Properties

Melting point	>300 °C
Boiling point	90-93 °C
bulk density	330kg/m3
density	1,69 g/cm3
Tg	175
refractive index	(25) 1.5300
refractive index	1.5300
storage temp.	2-8°C
solubility	H2O: soluble100mg/mL
form	powder
color	White to yellow-white
PH	3.0-5.0
biological source	synthetic (oragnic)
Water Solubility	Soluble in water.
Sensitive	Hygroscopic
Merck	14,7697
Stability:	Stable. Incompatible with strong oxidizing agents. Light sensitive. Hygroscopic.
Cosmetics Ingredients Functions	EMULSION STABILISING ANTISTATIC BINDING VISCOSITY CONTROLLING HAIR FIXING FILM FORMING
InChI	InChI=1S/C8H15NO/c1-3-7(2)9-6-4-5-8(9)10/h7H,3-6H2,1-2H3
InChIKey	FAAHNQAYWKTLFD-UHFFFAOYSA-N
SMILES	N1(C(C)CC)C(=O)CCC1
IARC	3 (Vol. 19, Sup 7, 71) 1987
EPA Substance Registry System	Polyvinylpyrrolidone (9003-39-8)

Safety Information

Safety Statements	22-24/25
WGK Germany	1
RTECS	TR8370000
Autoignition Temperature	440 °C
TSCA	TSCA listed
HS Code	39059990
Storage Class	11 - Combustible Solids
Hazardous Substances Data	9003-39-8(Hazardous Substances Data)
Toxicity	LD50 orally in Rabbit: > 2000 mg/kg

Product Application Of Polyvinylpyrrolidone CAS#9003-39-8

Although povidone is used in a variety of pharmaceutical formulations, it is primarily used in solid-dosage forms. In tableting, povidone solutions are used as binders in wet-granulation processes.Povidone is also added to powder blends in the dry form and granulated in situ by the addition of water, alcohol, or hydroalcoholic solutions. Povidone is used as a solubilizer in oral and parenteral formulations, and has been shown to enhance dissolution of poorly soluble drugs from solid-dosage forms. Povidone solutions may also be used as coating agents or as binders when coating active pharmaceutical ingredients on a support such as sugar beads.
Povidone is additionally used as a suspending, stabilizing, or viscosity-increasing agent in a number of topical and oral suspensions and solutions. The solubility of a number of poorly soluble active drugs may be increased by mixing with povidone.
Special grades of pyrogen-free povidone are available and have been used in parenteral formulations;

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