Isopropyl acetate CAS#108-21-4

Boiling point 

88.8 °C

density 

0.872 g/mL at 25 °C(lit.)

vapor density 

3.5 (vs air)

vapor pressure 

47 mm Hg ( 20 °C)

refractive index 

n20/D 1.377(lit.)

FEMA 

2926 | ISOPROPYL ACETATE

Fp 

62 °F

storage temp. 

Store below +30°C.

solubility 

1 M HCl: soluble50mg/mL, clear to slightly hazy, colorless

form 

Liquid

color 

Clear colorless

Odor

Pleasant, fruity; nonresidual.

Odor Threshold

0.16ppm

Odor Type

ethereal

biological source

synthetic

explosive limit

1.8%, 37°F

Water Solubility 

2.90 g/100 mL

FreezingPoint 

-73.4℃

Sensitive 

Moisture Sensitive

Merck 

14,5205

JECFA Number

305

BRN 

1740761

Exposure limits

TLV-TWA 250 ppm (～950 mg/m3) (ACGIH, MSHA, and OSHA); TLV-STEL 310 ppm (～1185 mg/m3) (ACGIH); IDLH 16,000 ppm (NIOSH).

Stability:

Stable. Flammable - note low flash point. Incompatible with strong oxidizing agents, strong acids, nitrates, alkali metals. May attack some plastics and rubber.

Cosmetics Ingredients Functions

SOLVENT

Cosmetic Ingredient Review (CIR)

Isopropyl acetate (108-21-4)

InChI

1S/C5H10O2/c1-4(2)7-5(3)6/h4H,1-3H3

InChIKey

JMMWKPVZQRWMSS-UHFFFAOYSA-N

SMILES

CC(C)OC(C)=O

LogP

1.03-1.18 at 20℃

Surface tension

21.89mN/m at 298.15K

CAS DataBase Reference

108-21-4(CAS DataBase Reference)

NIST Chemistry Reference

Acetic acid, 1-methylethyl ester(108-21-4)

EPA Substance Registry System

Isopropyl acetate (108-21-4)

Safety Information

Risk Statements 

11-36/37/38-67-66-36

Safety Statements 

16-26-36-33-29

RIDADR 

UN 1220 3/PG 2

WGK Germany 

1

RTECS 

AI4930000

Autoignition Temperature

894 °F

TSCA 

TSCA listed

HazardClass 

3

PackingGroup 

II

HS Code 

29153900

Storage Class

3 - Flammable liquids

Hazard Classifications

Eye Irrit. 2
Flam. Liq. 2
STOT SE 3

Hazardous Substances Data

108-21-4(Hazardous Substances Data)

Toxicity

LD50 orally in rats: 6.75 g/kg (Smyth)

IDLA

1,800 ppm