Adipic dihydrazide CAS#1071-93-8

CAS Number: 1071-93-8
Chemical Formula: C6H14N4O2
Synonyms:

Adipohydrazide
ADIPODIHYDRAZIDE
ADIPIC DIHYDRAZIDE

Appearance: White Powder

MOQ (Minimum Order Quantity): 1 FCL (Full Container Load)

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Product Details

Adipic dihydrazide CAS#1071-93-8

Adipic dihydrazide (ADH) is the most suitable hydrazide cross-linking agent, and ADH has been widely used in water-based paint emulsions in combination with diacetone acrylamide. ADH is weakly alkaline, and there is a possibility of agglomeration when solid ADH is added directly to the emulsion, so usually ADH should be dissolved in hot water before use.

Adipic dihydrazide Chemical Properties

Melting point	180-182 °C (lit.)
Boiling point	305.18°C (rough estimate)
density	1.2297 (rough estimate)
vapor pressure	0Pa at 25℃
refractive index	1.6700 (estimate)
Fp	150 °C
storage temp.	-20°C
solubility	H2O: 100 mg/mL
pka	12.93±0.35(Predicted)
form	Crystalline Powder
color	White to slightly yellow
Water Solubility	soluble
BRN	973863
Cosmetics Ingredients Functions	FRAGRANCE MOISTURISING
Cosmetic Ingredient Review (CIR)	Adipic dihydrazide (1071-93-8)
InChI	1S/C6H14N4O2/c7-9-5(11)3-1-2-4-6(12)10-8/h1-4,7-8H2,(H,9,11)(H,10,12)
InChIKey	IBVAQQYNSHJXBV-UHFFFAOYSA-N
SMILES	NNC(=O)CCCCC(=O)NN
LogP	-2.7 at 20℃
CAS DataBase Reference	1071-93-8(CAS DataBase Reference)
NIST Chemistry Reference	Adipic dihydrazide(1071-93-8)
EPA Substance Registry System	Hexanedioic acid, dihydrazide (1071-93-8)

Safety Information

Hazard Codes	Xi
Risk Statements	36/37/38
Safety Statements	22-24/25
WGK Germany	3
RTECS	AV1400000
Autoignition Temperature	360 °C
TSCA	TSCA listed
HazardClass	IRRITANT
HS Code	29280090
Storage Class	11 - Combustible Solids
Hazard Classifications	Aquatic Chronic 2

Product Application of Adipic dihydrazide CAS#1071-93-8

Adipic acid dihydrazide is a homobifunctional cross-linking reagent specific for aldehydes resulting in relatively stable hydrazone linkages. Adipic acid dihydrazide is typically, used in the linking of glycoproteins, such as antibodies, in a site specific fashion following periodate oxidation. Oxidation and coupling may conveniently be performed at pH 5.0 due to the low pKa of the hydrazide which avoids competition by primary amines.

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