Adipic acid CAS#124-04-9

CAS Number: 124-04-9
Chemical Formula: C6H10O4
Synonyms:

RARECHEM AL BO 0180
AKOS BBS-00004308
ADIPIC ACID

Appearance: White Powder

MOQ (Minimum Order Quantity): 1 FCL (Full Container Load)

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Product Details

Adipic acid is a crystalline powder with practically no odor. It has the lowest acidity of any of the acids commonly used in foods and has excellent buffering capacity in the range of pH 2.5 to 3.0. Like succinic and fumaric acid, adipic acid is practically nonhygroscopic. Its addition to foods imparts a smooth, tart taste. In grape-flavored products, it adds a lingering supplementary flavor and gives an excellent set to food powders containing gelatin. As a result, adipic acid has found a wide number of uses as an accidulant in dry powdered food mixtures, especially in those products having delicate flavors and where addition of tang to the flavor is undesirable.

Adipic acid Chemical Properties

Melting point	151-154 °C(lit.)
Boiling point	265 °C100 mm Hg(lit.)
bulk density	700kg/m3
density	1,36 g/cm3
vapor density	5 (vs air)
vapor pressure	1 mm Hg ( 159.5 °C)
refractive index	1.4880
FEMA	2011 \| ADIPIC ACID
Fp	385 °F
storage temp.	Store below +30°C.
solubility	methanol: 0.1 g/mL, clear, colorless
pka	4.43(at 25℃)
form	Solid
color	White
Odor	wh. monoclinic prisms, pract. odorless
PH	3.74(1 mM solution);3.22(10 mM solution);2.71(100 mM solution);
biological source	synthetic
Water Solubility	1.44 g/100 mL (15 ºC)
Merck	14,162
JECFA Number	623
BRN	1209788
Dielectric constant	1.8（Ambient）
Exposure limits	ACGIH: TWA 5 mg/m3
Stability:	Stable. Substances to be avoided include ammonia, strong oxidizing agents.
Major Application	flavors and fragrances
Cosmetics Ingredients Functions	FRAGRANCE BUFFERING
Cosmetic Ingredient Review (CIR)	Adipic acid (124-04-9)
InChI	1S/C6H10O4/c7-5(8)3-1-2-4-6(9)10/h1-4H2,(H,7,8)(H,9,10)
InChIKey	WNLRTRBMVRJNCN-UHFFFAOYSA-N
SMILES	OC(=O)CCCCC(O)=O
LogP	0.09 at 25℃
CAS DataBase Reference	124-04-9(CAS DataBase Reference)
NIST Chemistry Reference	Hexanedioic acid(124-04-9)
EPA Substance Registry System	Adipic acid (124-04-9)

Safety Information

Hazard Codes	Xi
Risk Statements	36-41
Safety Statements	26-39-24/25
RIDADR	UN3077
WGK Germany	1
RTECS	AU8400000
Autoignition Temperature	788 °F
TSCA	TSCA listed
HazardClass	9
HS Code	29171210
Storage Class	11 - Combustible Solids
Hazard Classifications	Eye Dam. 1
Hazardous Substances Data	124-04-9(Hazardous Substances Data)
Toxicity	LD50 orally in Rabbit: 5700 mg/kg LD50 dermal Rabbit > 7940 mg/kg

Product Application Of Adipic acid CAS#124-04-9

Adipic acid is used as an acidifying and buffering agent in intramuscular, intravenous and vaginal formulations. It is also used in food products as a leavening, pH-controlling, or flavoring agent.
Adipic acid has been incorporated into controlled-release formulation matrix tablets to obtain pH-independent release for both weakly basicand weakly acidic drugs.It has also been incorporated into the polymeric coating of hydrophilic monolithic systems to modulate the intragel pH, resulting in zero-order release of a hydrophilic drug.The disintegration at intestinal pH of the enteric polymer shellac has been reported to improve when adipic acid was used as a pore-forming agent without affecting release in the acidic media.Other controlled-release formulations have included adipic acid with the intention of obtaining a late-burst release profile.

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