4-Morpholineethanesulfonic acid CAS# 4432-31-9

  • CAS Number:  4432-31-9

  • Chemical Formula:  C6H13NO4S

  • Synonyms:

    • HUMNDME;ME1

    • ANTI-ME1 antibody produced in mouse

    • MES(2-(n-Morpholino)-ethanesulfonic  acid), Free Acid

    Appearance: White Powder

  • MOQ (Minimum Order Quantity): 1 FCL (Full Container Load)


Product Details

4-Morpholineethanesulfonic acid CAS#4432-31-9

MES is one of the Good′s buffers, the most extensively used biological buffers. MES is a zwitterionic N-substituted aminosulfonic acid with a morpholinic ring. It does not form complexes with majority of the metals used in environmental and biological studies. It is easily soluble in water and has minimum lipid solubility, making it impermeable to membranes.

4-Morpholineethanesulfonic acid Chemical Properties

Melting point 

>300 °C(lit.)

Boiling point 

102°C

density 

1.208 (estimate)

refractive index 

1.5500 (estimate)

storage temp. 

2-8°C

solubility 

H2O: 0.5 M at 20 °C, clear

form 

Powder

pka

pKa at 0.1M ionic: 0°, 6.38; 20°, 6.15; 37°, 5.98; pKa1 1.99; pKa2 6.21; pKa/°C -0.011

color 

White

PH

2.5-4.0 (25℃ in neat)

PH Range

5.5 - 6.7

Water Solubility 

185.2g/L at 20℃

λmax

λ: 260 nm Amax: 0.01
λ: 280 nm Amax: 0.01

Merck 

13,5929

BRN 

6350956

Stability:

Stable. Incompatible with strong oxidizing agents.

InChIKey

SXGZJKUKBWWHRA-UHFFFAOYSA-N

LogP

-2.2 at 20℃

CAS DataBase Reference

4432-31-9(CAS DataBase Reference)

EPA Substance Registry System

4-Morpholineethanesulfonic acid (4432-31-9)


Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

26-36-24/25-22

WGK Germany 

1

RTECS 

QE9104530

TSCA 

TSCA listed

HS Code 

29349990


Product Application of 4-Morpholineethanesulfonic acid CAS#4432-31-9

4-Morpholineethanesulfonic acid (MES) is one of the good′s buffers, and the most extensively application is biological buffers. MES is a zwitterionic N-substituted aminosulfonic acid with a morpholinic ring and it does not form complexes with the majority of the metals used in environmental and biological studies. It is easily soluble in water and has minimum lipid solubility, making it impermeable to membranes. MES has been also used as a component of the elution buffer used to elute plasma from α2-macroglobulin affinity column. It has been used as an activation buffer during antibody conjugation to microparticles and it has been used in the functionalization of microchannels during the creation of microfluidic-integrated surface plasmon resonance (SPR) platform for pathogen detection.


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