β-Nicotinamide Mononucleotide CAS#1094-61-7

CAS Number: 1094-61-7
Chemical Formula: C11H15N2O8P
Synonyms:

BETA-NMN
BETA-NICOTINAMIDE MONONUCLEOTIDE
NICOTINAMIDE RIBOTIDE

Appearance: White Powder

MOQ (Minimum Order Quantity): 1 FCL (Full Container Load)

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Product Details

β-Nicotinamide Mononucleotide CAS#1094-61-7

Nicotinamide mononucleotide (NMN), a product of the NAMPT reaction and a key NAD+ intermediate, ameliorates glucose intolerance by restoring NAD+ levels in HFD-induced T2D mice. NMN also enhances hepatic insulin sensitivity and restores gene expression related to oxidative stress, inflammatory response, and circadian rhythm, partly through SIRT1 activation. NMN is used for studying binding motifs within RNA aptamers and ribozyme activation processes involving β-nicotinamide mononucleotide (β-NMN)-activated RNA fragments.
β-Nicotinamide mononucleotide (β-NMN) is an intermediate in the nicotinamide phosphoribosyltransferase (NAMPT)-catalyzed biosynthesis of nicotinamide adenine dinucleotide (NAD+). NAMPT mediates the condensation of nicotinamide with 5-phosphoribosyl-1-pyrophosphate to produce β-NMN. β-NMN adenyltransferase subsequently converts β-NMN to NAD+.

β-Nicotinamide Mononucleotide Chemical Properties

Melting point	166 °C(dec.)
storage temp.	-20°C
solubility	DMSO (Slightly, Heated), Methanol (Slightly), Water (Slightly)
form	Solid
color	White to Yellow
Merck	13,6697
BRN	3570187
Stability:	Very Hygroscopic
Cosmetics Ingredients Functions	ANTIOXIDANT
InChI	InChI=1/C11H15N2O8P/c12-10(16)6-2-1-3-13(4-6)11-9(15)8(14)7(21-11)5-20-22(17,18)19/h1-4,7-9,11,14-15H,5H2,(H3-,12,16,17,18,19)/t7-,8-,9-,11-/s3
InChIKey	DAYLJWODMCOQEW-TURQNECASA-N
SMILES	O[C@@H]1[C@@H]([C@@H](COP(O)([O-])=O)O[C@H]1[N+]1=CC=CC(C(=O)N)=C1)O \|&1:1,2,3,11,r\|

Safety Information

WGK Germany	3
F	8-10-21
HS Code	2934999090
Storage Class	11 - Combustible Solids

Product Application Of β-Nicotinamide Mononucleotide CAS#1094-61-7

β-Nicotinamide mononucleotide (NMN) is a product of the extracellular Nicotinamide phosphoribosyltransferase (eNAMPT) reaction and a key NAD+ intermediate. It ameliorates glucose intolerance by restoring NAD+ levels in HFD-induced T2D mice . It also enhances hepatic insulin sensitivity and restores gene expression related to oxidative stress, inflammatory response, and circadian rhythm, partly through SIRT1 activation. It is used to study binding motifs within RNA aptamers and ribozyme activation processes involving β-nicotinamide mononucleotide (β-NMN)-activated RNA fragments.

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