2-Deoxy-D-glucose CAS#154-17-6

CAS Number: 154-17-6
Chemical Formula: C6H12O5
Synonyms:

2-deoxy-d-arabino-hexos
2-deoxy-d-glucos
2-deoxy-d-mannose

Appearance: White Solid

MOQ (Minimum Order Quantity): 1 FCL (Full Container Load)

Contact Now E-Mail Telephone WhatsApp

Product Details

2-Deoxy-D-glucose CAS#154-17-6

2-Deoxy-D-glucose (154-17-6) is a synthetic glucose analog with extensive biological effects. It is commonly thought of as an inhibitor of glycolysis, but its metabolic effects are wide-ranging. 2-Deoxy-D-glucose competitively inhibits glucose uptake via its metabolite 2-Deoxy-D-glucose-6-phosphate, which inhibits hexokinase and phosphoglucose-isomerase leading to decreased ATP production, cell cycle blockage, decreased cell growth and ultimately cell death.1,2

2-Deoxy-D-glucose Chemical Properties

Melting point	146-147 °C(lit.)
alpha	45.5 º (c=2, H2O)
Boiling point	211.61°C (rough estimate)
density	1.1738 (rough estimate)
refractive index	46.5 ° (C=1, H2O)
storage temp.	2-8°C
solubility	H2O: 50 mg/mL, clear, colorless to faintly yellow
pka	pK1:12.52 (25°C)
form	crystalline
color	white
Optical Rotation	+38.5 → +45.9
biological source	synthetic
Water Solubility	Soluble in water.
Merck	14,2904
BRN	1723331
Stability:	Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 1 month. Solutions in water are not stable and must be used within 1 working day.
InChI	1S/C6H12O5/c7-2-1-4(9)6(11)5(10)3-8/h2,4-6,8-11H,1,3H2/t4-,5-,6+/m1/s1
InChIKey	PMMURAAUARKVCB-CEZCPVKQSA-N
SMILES	OC[C@@H](O)[C@@H](O)[C@H](O)CC=O
LogP	-1.460 (est)
CAS DataBase Reference	154-17-6(CAS DataBase Reference)
EPA Substance Registry System	D-arabino-Hexose, 2-deoxy- (154-17-6)

Safety Information

Hazard Codes	Xn,Xi
Risk Statements	20/21/22-36/37/38
Safety Statements	24/25-37/39-36-26
WGK Germany	3
RTECS	MQ3325000
F	3-10
TSCA	TSCA listed
HS Code	29400090
Storage Class	11 - Combustible Solids
Hazardous Substances Data	154-17-6(Hazardous Substances Data)

Product Application Of 2-Deoxy-D-glucose CAS#154-17-6

2-Deoxy-D-glucose is act as a culture media part in molecular genetics and as a targeted optical imaging agent for fluorescent in vivo imaging. It finds an application in glucoprivic feeding research to invoke and study the processes of counter-regulatory response (CRR). It is utilized in the development of anti-cancer approaches like oxidative stress, radio and chemosensitization.

Fact Factory and Equipment Show

Gardenia Yellow#94238-00-3