Glycyrrhizic acid ammonium salt CAS#53956-04-0

Products Description of Glycyrrhizic acid ammonium salt CAS#53956-04-0

Ammonium Glycyrrhizinate‌ exhibits an intense sweet taste, approximately ‌200 times sweeter than sucrose‌. It is commonly used as a ‌sweetener in food additives‌, applied in products such as canned meats, seasonings, candies, biscuits, preserved fruits, and beverages. Monoammonium glycyrrhizinate demonstrates strong affinity for hepatic sterol-metabolizing enzymes (ref: Chemicalbook), thereby ‌inhibiting the inactivation of cortisol and aldosterone‌. Upon administration, it manifests significant ‌glucocorticoid-like effects‌, including anti-inflammatory actions, anti-allergic properties, and protection of membrane structures, ‌without exhibiting the typical side effects associated with corticosteroids‌.

Parameters

Melting point	>200°C (dec.)
Boiling point	768.56°C (rough estimate)
density	1.1846 (rough estimate)
FEMA	2528 | GLYCYRRHIZIN, AMMONIATED (GLYCYRRHIZA SPP.)
refractive index	49 ° (C=1.5, EtOH)
storage temp.	2-8°C
solubility	Slightly soluble in water, very slightly soluble in anhydrous ethanol, practically insoluble in acetone. It dissolves in dilute solutions of acids and of alkali hydroxides.
form	Powder or Crystals
color	Yellow to yellow-green
Odor	bland
optical activity	[α]20/D +48±4°, c = 1% in ethanol: water (1:1)
BRN	3897076
Stability:	Hygroscopic
InChIKey	ILRKKHJEINIICQ-YDYGGSECSA-N
LogP	-0.9
CAS DataBase Reference	53956-04-0
EPA Substance Registry System	.alpha.-D-Glucopyranosiduronic acid, (3.beta.,20.beta.)-20-carboxy-11-oxo-30-norolean-12-en-3-yl 2-O-.beta.-D-glucopyranuronosyl-, monoammonium salt (53956-04-0)

Safety Information

RIDADR	UN 3077 9 / PGIII
WGK Germany	2
RTECS	LZ6500000
F	3-10
HS Code	29389090

Product Application of  Glycyrrhizic acid ammonium salt CAS#53956-04-0

Ammonium Glycyrrhizinate is used in the synthesis of polyion complex nanocarriers which may act as a template for the design of other negatively charged water-soluble drugs. Particularly for anti-infl ammatory drugs with which Ammonium Glycyrrhizinate is associated,Glycyrrhizic acid ammonium salt is a flavoring and sweetening agent obtained from licorice flavonoids. It has a slight licorice flavor and an intense and rounded sweetness. It is soluble in water, glycerin, and propylene glycol and has good thermal stability but can degrade under prolonged heating. It is stable over a ph of 3.5–9 but could precipitate below ph of 3.5. It can be used in beverages, desserts, confectionary products, soups, and dressings.

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Inventory 2-3 working days New production 7-10 working days