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Dexamethasone CAS#50-02-2
CAS Number: 50-02-2
Chemical Formula:C22H29FO5
Synonyms:
DEXAMETHASONE BASE
DEXAMETHASONUM
DEXAMETHASON
Appearance: Off-white powder
HS Code:29372210
MOQ (Minimum Order Quantity): 1 FCL (Full Container Load)
Products Description of Dexamethasone CAS#50-02-2
Dexamethasone is one of the commonly used drugs in clinical practice. It is often used in combination with other drugs in clinical practice. It has anti-inflammatory, anti-toxic and anti-allergic effects. However, it has no therapeutic effect on the disease and can only reduce or inhibit the manifestation of inflammation. Therefore, it must be noted when using it clinically. Generally, it is not used alone and must be used in combination with other drugs to play a better role.
Parameters
| Melting point | 262-264 °C (lit.) |
| alpha | 75 º (c=1, dioxane) |
| Boiling point | 568.2±50.0 °C(Predicted) |
| density | 1.1283 (estimate) |
| refractive index | 76 ° (C=1, Dioxane) |
| Fp | 9℃ |
| storage temp. | 2-8°C |
| solubility | ethanol: 1 mg/mL |
| form | powder |
| pka | 12.13±0.70(Predicted) |
| color | off-white |
| biological source | synthetic (organic) |
| Water Solubility | 10 mg/100 mL (25 ºC) |
| Sensitive | Light Sensitive |
| Merck | 142943 |
| BRN | 2066651 |
| BCS Class | 1 (CLogP), 3 (LogP) |
| Stability: | Stable. Combustible. Incompatible with strong oxidizing agents, strong bases, acid anhydrides, acid chlorides. May be light sensitive. |
| InChIKey | UREBDLICKHMUKA-CXSFZGCWSA-N |
| CAS DataBase Reference | 50-02-2(CAS DataBase Reference) |
| NIST Chemistry Reference | Prednisolone, 9alpha-fluoro-16alpha-methyl-(50-02-2) |
| EPA Substance Registry System | Dexamethasone (50-02-2) |
| Safety Information | |
| Hazard Codes | Xi,Xn,T,F |
| Risk Statements | 43-40-36/37/38-20/21/22-42/43-39/23/24/25-23/24/25-11 |
| Safety Statements | 36/37-45-36-26-22-16 |
| RIDADR | UN1230 - class 3 - PG 2 - Methanol, solution |
| WGK Germany | 2 |
| RTECS | TU3980000 |
| TSCA | Yes |
| HS Code | 29372210 |
| Hazardous Substances Data | 50-02-2(Hazardous Substances Data) |
| Toxicity | LD50 oral in rat: > 3gm/kg |
Product Application of Dexamethasone CAS#50-02-2
Dexamethasone (dexamethasone sodium phosphate EP impurity A) is a glucocorticoid used as an anti-inflammatory agent. Dexamethasone regulates the survival, growth and differentiation of T cells. Dexamethasone inhibits the induction of nitric oxide synthase.
It is mainly used for anti-inflammatory and anti-allergic purposes, and is suitable for rheumatoid arthritis and other collagen diseases.
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