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Carbamazepine CAS#298-46-4
CAS Number: 298-46-4
Chemical Formula: C15H12N2O
Synonyms:
Oxcarbazepine IMpurity A
CarbaMazepine (D10, 98%)
CarbaMazepine (D10, 98%) 100 ug/Ml In MeOH
Appearance: White crystal
HS Code:29339900
MOQ (Minimum Order Quantity): 1 FCL (Full Container Load)
Products Description of Carbamazepine CAS#298-46-4
Carbamazepine is a white or off-white crystalline powder. It belongs to the dibenzazepine class of antiepileptic drugs and has similar antiepileptic effects as phenytoin sodium. It is most effective for psychomotor seizures, and is also effective for grand mal seizures, localized seizures, and mixed seizures. Carbamazepine is better than phenytoin sodium in the treatment of peripheral neuropathy and can be used for trigeminal neuralgia and glossopharyngeal neuralgia. It can also be used to treat arrhythmias and diabetes insipidus.
Parameters
| Melting point | 191-192 °C (lit.) |
| Boiling point | 378.73°C (rough estimate) |
| density | 1.1099 (rough estimate) |
| refractive index | 1.5906 (estimate) |
| Fp | 9℃ |
| storage temp. | 2-8°C |
| solubility | 45% (w/v) aq 2-hydroxypropyl-β-cyclodextrin: soluble29mg/mL |
| form | Crystals |
| pka | 13.94±0.20(Predicted) |
| color | Almost white |
| Water Solubility | pract. insoluble |
| Merck | 141781 |
| BCS Class | 2 |
| LogP | 2.45 |
| CAS DataBase Reference | 298-46-4(CAS DataBase Reference) |
| NIST Chemistry Reference | Carbamazepine(298-46-4) |
| EPA Substance Registry System | 5H-Dibenz[b,f]azepine-5-carboxamide (298-46-4) |
| Safety Information | |
| Hazard Codes | Xn,T,F |
| Risk Statements | 42/43-22-20/21/22-39/23/24/25-23/24/25-11 |
| Safety Statements | 37-24-22-36/37/39-36-45-36/37-16 |
| RIDADR | UN1230 - class 3 - PG 2 - Methanol, solution |
| WGK Germany | 2 |
| RTECS | HN8225000 |
| HS Code | 29339900 |
| Hazardous Substances Data | 298-46-4(Hazardous Substances Data) |
| Toxicity | LD50 orally in mice, rats: 3750, 4025 mg/kg (Stenger, Roulet) |
Product Application of Carbamazepine CAS#298-46-4
Carbazine belongs to the dibenzazepine class of antiepileptic drugs, and has antiepileptic effects similar to phenytoin sodium. It is most effective for psychomotor seizures, and is also effective for grand mal seizures, localized seizures, and mixed seizures. This product is better than phenytoin sodium in the chemicalbook of anti-peripheral neuropathy, and can be used for trigeminal neuralgia and glossopharyngeal neuralgia. It can also be used to treat arrhythmias and diabetes insipidus. The oral LD50 for mice is 3750mg/kg, and that for rats is 4025mg/kg.
Anticonvulsant, used to treat grand mal seizures and psychomotor epilepsy, and can also treat trigeminal neuralgia
Anticonvulsant; ligand, used for benzodiazepine regulatory sites of GABAA receptors. Sodium ion channel inhibitor.
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