Acetaminophen CAS#103-90-2

CAS Number: 103-90-2

Chemical Formula: C8H9NO2

Synonyms:

PARACETAMOL BP2001

PARACETAMOL POWDER

PARACETAMOL POWDER BP

Appearance: White crystal

HS Code:29242930

MOQ (Minimum Order Quantity): 1 FCL (Full Container Load)

Product Details

Products Description of Acetaminophen CAS#103-90-2

The chemical name of acetaminophen is N-(4-hydroxyphenyl)acetamide, and its trade name is paracetamol, which belongs to the acetanilide antipyretic analgesic. It was first synthesized by Morse in 1878 and first used clinically by Von Mering in 1893. It became an over-the-counter drug in the United States in 1955, and my country began to produce it at the end of the Chemicalbook in the 1950s. It appears as white crystals or crystalline powder, with a melting point of 168-172°C, odorless, slightly bitter, easily soluble in hot water or ethanol, soluble in acetone, and almost insoluble in cold water and petroleum ether. It is stable below 45°C, but if exposed to humid air, it will hydrolyze into para-aminophenol, and then further oxidize, and the color will gradually turn pink, brown, and finally black, so it should be stored in a cool and dry place.


Parameters


Melting point 

168-172 °C(lit.)

Boiling point 

273.17°C (rough estimate)

density 

1,293 g/cm3

vapor pressure 

0.008Pa at 25℃

refractive index 

1.5810 (rough estimate)

Fp 

11 °C

storage temp. 

Inert atmosphere,Room Temperature

solubility 

ethanol: soluble0.5M, clear, colorless

form 

Crystals or Crystalline Powder

pka

9.86±0.13(Predicted)

color 

White

PH Range

5.5 - 6.5 (H?O, 20 °C) (saturated solution)

PH

5.5-6.5 (H2O, 20℃)(saturated solution)

Odor

odorless

explosive limit

15%(V)

Water Solubility 

14 g/L (20 ºC)

Merck 

14,47

BRN 

2208089

BCS Class

3,4

InChIKey

RZVAJINKPMORJF-UHFFFAOYSA-N

LogP

1.098 at 25℃

CAS DataBase Reference

103-90-2(CAS DataBase Reference)

NIST Chemistry Reference

Acetaminophen(103-90-2)

IARC

3 (Vol. 50, 73) 1999

EPA Substance Registry System

Acetaminophen (103-90-2)

Safety Information


Hazard Codes 

Xn,T,F

Risk Statements 

22-36/37/38-52/53-36/38-40-39/23/24/25-23/24/25-11

Safety Statements 

26-36-61-37/39-22-45-36/37-16-7

RIDADR 

UN 3077 9/PG III

WGK Germany 

1

RTECS 

AE4200000

Autoignition Temperature

540 °C

TSCA 

Yes

HazardClass 

9

PackingGroup 

III

HS Code 

29242930

Hazardous Substances Data

103-90-2(Hazardous Substances Data)

Toxicity

LD50 in mice (mg/kg): 338 orally (Starmer), 500 i.p. (Dahlin, Nelson

Product Application of Acetaminophen CAS#103-90-2

It is mainly used for fever and headache caused by colds and to relieve mild and moderate pain, such as joint pain, muscle pain, neuralgia, migraine, dysmenorrhea, cancer pain and postoperative analgesia. It can also be used for patients who are allergic to, intolerant of or unsuitable for aspirin, such as patients with chickenpox, hemophilia and other bleeding diseases (including patients taking anticoagulant therapy), as well as patients with mild peptic ulcer and gastritis.



Factory and Equipment Show

Acetaminophen CAS#103-90-2


Fast delivery time

Inventory 2-3 working days New production 7-10 working days


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