Potassium bis(trimethylsilyl)amide CAS#40949-94-8
CAS Number: 40949-94-8
Chemical Formula: C6H18KNSi2
Synonyms:
POTASSIUM HEXAMETHYLDISLAZANE
POTASSIUM HEXAMETHYLDISILAZIDE
1,1,1,3,3,3-HEXAMETHYLDISILAZANE POTASSIUM SALT
MOQ (Minimum Order Quantity): 1 FCL (Full Container Load)
Appearance: Yellow Liquid
Potassium bis(trimethylsilyl)amide CAS#40949-94-8
This product, 1.0 M in 2-methyltetrahydrofuran aligns with "Safer Solvents and Auxiliaries", "Use of Renewable Feedstocks" and "Inherently Safer Chemistry for Accident Prevention".
Potassium bis(trimethylsilyl)amide Chemical Properties |
Melting point | 194-195°C |
Boiling point | 111 °C |
density | 0.877 g/mL at 25 °C |
vapor density | 3.2 (vs air) |
vapor pressure | 54 mm Hg ( 25 °C) |
refractive index | 1.4920 |
Fp | 45 °F |
storage temp. | Refrigerator |
solubility | Miscible with terahydrofuran, ether, benzene and toluene. |
form | Liquid |
color | clear to slightly hazy yellow |
Specific Gravity | 0.877 |
Water Solubility | Reacts with water. |
Sensitive | Moisture Sensitive |
Hydrolytic Sensitivity | 8: reacts rapidly with moisture, water, protic solvents |
BRN | 4006754 |
InChI | 1S/C6H18NSi2.K/c1-8(2,3)7-9(4,5)6;/h1-6H3;/q-1;+1 |
InChIKey | IUBQJLUDMLPAGT-UHFFFAOYSA-N |
SMILES | C[Si](C)(C)N([K])[Si](C)(C)C |
CAS DataBase Reference | 40949-94-8(CAS DataBase Reference) |
EPA Substance Registry System | Silanamine, 1,1,1-trimethyl-N-(trimethylsilyl)-, potassium salt (1:1) (40949-94-8) |
Safety Information |
Hazard Codes | C,F,Xn |
Risk Statements | 14-34-67-65-63-48/20-11-40-36/37/38-19-37 |
Safety Statements | 26-36/37/39-45-62-43-46-16-36/37 |
RIDADR | UN 3263 8/PG 3 |
WGK Germany | 3 |
F | 1-3-10 |
TSCA | TSCA listed |
HazardClass | 3 |
PackingGroup | II |
HS Code | 29319090 |
Storage Class | 8A - Combustible corrosive hazardous materials |
Hazard Classifications | Eye Dam. 1 |
Product Application of Potassium bis(trimethylsilyl)amide CAS#40949-94-8
Potassium Bis(trimethylsilyl)amide (1M in THF) is used in the preparation of 5-azacytidine, an antineoplastic drug. Also applied in the preparation of β3-AR agonists used in anti-stress formulations. It is also used as a reagent in the preparation of lanthanide complexes employed in selective cyclization reactions.
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