Folic acid CAS#59-30-3

alpha 

20 º (c=1, 0.1N NaOH)

Boiling point 

552.35°C (rough estimate)

bulk density

110kg/m3

density 

1.4704 (rough estimate)

refractive index 

1.6800 (estimate)

storage temp. 

2-8°C

solubility 

boiling water: soluble1%

pka

pKa 2.5 (Uncertain)

form 

Crystalline Powder

color 

Yellow to orange

Odor

Odorless

PH

4.0-4.8 (25°C, 100g/L in H2O)

PH Range

4

biological source

synthetic (organic)

Water Solubility 

1.6 mg/L (25 ºC)

Merck 

14,4221

BRN 

100781

BCS Class

3

Stability:

Stable. Incompatible with heavy metal ions, strong oxidizing agents, strong reducing agents. Solutions may be light and heat sensitive.

Cosmetics Ingredients Functions

SKIN CONDITIONING

InChIKey

OVBPIULPVIDEAO-LBPRGKRZSA-N

SMILES

NC(N1)=NC(C2=C1N=CC(CNC3=CC=C(C(N[C@@H](CCC(O)=O)C(O)=O)=O)C=C3)=N2)=O

LogP

-0.990 (est)

CAS DataBase Reference

59-30-3(CAS DataBase Reference)

NIST Chemistry Reference

Folic acid(59-30-3)

EPA Substance Registry System

L-Glutamic acid, N-[4-[[(2-amino-3,4-dihydro-4-oxo-6-pteridinyl)methyl]amino]benzoyl]- (59-30-3)

Safety Information

Safety Statements 

24/25

WGK Germany 

1

RTECS 

LP5425000

F 

8

TSCA 

TSCA listed

HS Code 

29362900

Storage Class

11 - Combustible Solids

Hazardous Substances Data

59-30-3(Hazardous Substances Data)

Toxicity

A water soluble vitamin required in the diet of mammals. Sulfonamide drugs are selectively toxic to bacteria because they inhibit the incorporation of p-aminobenzoic acid into folic acid, a biosynthetic process in bacteria. Folic acid deficiency adversely affects prenatal development in humans. Dietary supplementation with folic acid dramatically reduces the incidence of neural tube defects in humans. Folic acid deficiency may also contribute to the causes of megaloblastic macrocytic anemia and a consequence of this is that this disease can be induced, as a side effect, when methotrexate, a folic acid antagonist, is used in cancer chemotherapy