Dextran CAS#9004-54-0
CAS Number: 9004-54-0
Chemical Formula: C17H32O10
Synonyms:
DEXTRAN,250,000,POWDER
DEXTRAN,150,000,POWDER
POLY[(1,6)-ALPHA-D-GLUCOSE]
MOQ (Minimum Order Quantity): 1 FCL (Full Container Load)
Appearance: White Powder
Dextran CAS#9004-54-0
Dextran, a glucose polymer composed predominantly of ol-1,6-glucopyranosidic linkages, is produced from sucrose by Leuconostoc mesenteroides and related organisms and from dextrins by other bacteria.
Dextran is used in a bead form to aid in bioreactor applications, some size-exclusion chromatography matrices and in osmotic stress technique study involved in biological molecules. It can be used as a stabilizing coating to protect metal nanoparticles from oxidation.
Dextrans are long-chain glucose polysaccharides of various relative molecular masses. Dextran 70 (relative molecular mass 70 000) is retained in the intravascular space where, like albumin, it contributes to the colloid oncotic pressure of plasma. Unlike albumin, dextran 70, when given in large amounts, prevents platelet aggregation and facilitates fibrinolysis.
Dextran Chemical Properties |
Melting point | 483 °C (decomp) |
alpha | 198 º |
density | 1.00-1.20g/mL |
refractive index | 185 ° (C=6, H2O) |
storage temp. | 2-8°C |
solubility | H2O: soluble50mg/mL, clear to very slightly hazy, colorless to faintly yellow |
form | Solid |
color | White to slightly off-white |
PH | 2 - 10 |
biological source | bacterial (Leuconostoc mesenteroides) |
Optical Rotation | +208 to +233 (formaldehyde) |
Water Solubility | Soluble in water, dimethyl sulfoxide, ethylene glycol and glycerol. |
Merck | 14,2948 |
Stability: | Stable. Keep dry. Incompatible with strong oxidizing agents. |
Major Application | food and beverages |
Cosmetics Ingredients Functions | SKIN CONDITIONING |
Cosmetic Ingredient Review (CIR) | Dextran (9004-54-0) |
InChI | 1S/C18H32O16/c19-1-5(21)9(23)10(24)6(22)3-31-17-16(30)14(28)12(26)8(34-17)4-32-18-15(29)13(27)11(25)7(2-20)33-18/h1,5-18,20-30H,2-4H2 |
InChIKey | FZWBNHMXJMCXLU-UHFFFAOYSA-N |
LogP | -4.259 (est) |
EPA Substance Registry System | Dextran (9004-54-0) |
Absorption | ≤0.05 at 375nm in H2O at 10% |
Safety Information |
Hazard Codes | Xn,Xi |
Risk Statements | 20/21/22-36/37/38 |
Safety Statements | 24/25-37/39-36-26 |
WGK Germany | 2 |
RTECS | HH9230000 |
F | 3 |
TSCA | TSCA listed |
HS Code | 39139000 |
Storage Class | 11 - Combustible Solids |
Toxicity | LD50 oral in rat: > 3gm/kg |
Product Application of Dextran CAS#9004-54-0
Dextran is a polysaccharide with water-binding properties. It is also used to control product viscosity. Some studies indicate a capacity to enhance the anti-aging activity of formulations containing weak acids, as well as to reduce possible skin irritation arising from such acids.
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