Magnesium Stearate CAS#557-04-0
CAS Number: 557-04-0
Chemical Formula: C36H70MgO4
Synonyms:
stearatedemagnesium
MAGNESIUM STEARATE
MAGNESIUM OCTADECANOATE
MOQ (Minimum Order Quantity): 1 FCL (Full Container Load)
Appearance: White Powder
Magnesium Stearate CAS#557-04-0
Magnesium stearate has been widely used for many decades in the food industry as an emulsifier, binder and thickener, as well as an anticaking, lubricant, release, and antifoaming agent. It is present in many food supplements, confectionery, chewing gum, herbs and spices, and baking ingredients. Magnesium stearate is also commonly used as an inactive ingredient in the production of pharmaceutical tablets, capsules and powders. The main reason for its good lubricating properties is its hydrophobic nature and an ability to reduce friction between tablets and die wall during the ejection process.
Magnesium stearate can be regarded as being non-toxic, the United States, Germany and Japan allow it to be applied to products being contact with food. However, it doesn’t have wide application to be applied as PVC heat stabilizers. In China and some other countries Pharmacopoeia, there are always records of this specie. The pharmacopeia has also made provisions on the magnesium content, moisture, heavy metals, iron, sulfate and chloride content.
| Magnesium stearate Chemical Properties |
| Melting point | 200 °C (lit.) |
| density | 1.028g/cm3 |
| storage temp. | Inert atmosphere,Room Temperature |
| solubility | alcohol: insoluble |
| form | Fine Powder |
| color | White |
| Odor | wh. soft oily powd., tasteless, odorless |
| PH | 7 (H2O) (slurry) |
| Water Solubility | Insoluble |
| Merck | 14,5690 |
| BRN | 3919702 |
| Exposure limits | ACGIH: TWA 10 mg/m3; TWA 3 mg/m3 |
| Stability: | Stable. Incompatible with strong oxidizing agents. |
| Cosmetics Ingredients Functions | MOISTURISING ANTICAKING BULKING COLORANT |
| InChIKey | DRJIJXNWSSRTTE-UHFFFAOYSA-M |
| LogP | 8.216 (est) |
| CAS DataBase Reference | 557-04-0(CAS DataBase Reference) |
| EPA Substance Registry System | Magnesium stearate (557-04-0) |
| Safety Information |
| Hazard Codes | Xi |
| Risk Statements | 36/37/38 |
| Safety Statements | 26-37/39 |
| WGK Germany | - |
| RTECS | WI4390000 |
| TSCA | Yes |
| HS Code | 29157030 |
| Hazardous Substances Data | 557-04-0(Hazardous Substances Data) |
| Toxicity | LD50 orally in Rabbit: > 2000 mg/kg |
Product Application of Magnesium Stearate CAS#557-04-0
Magnesium stearate is often used as a anti-adherent in the manufacture of medical tablets, capsules and powders. In this regard, the substance is also useful, because it has lubricating properties, preventing ingredients from sticking to manufacturing equipment during the compression of chemical powders into solid tablets; magnesium stearate is the most commonly used lubricant for tablets. Studies have shown that magnesium stearate may affect the release time of the active ingredients in tablets, etc., but not that it reduces the overall bioavailability of those ingredients. As a food additive or pharmaceutical excipient, its E number is E470b.
Magnesium stearate is also used to bind sugar in hard candies like mints, and is a common ingredient in baby formulas. In pure powder form, the substance can be a dust explosion hazard, although this issue is effectively insignificant beyond the manufacturing plants using it.
Magnesium stearate is manufactured from both animal and vegetable oils. Some nutritional supplements specify that the magnesium stearate used is sourced from vegetables.
Magnesium stearate is a major component of "bathtub rings." When produced by soap and hard water, magnesium stearate and calcium stearate both form a white solid insoluble in water, and are collectively known as "soap scum.".
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