Acetylsalicylic acid CAS# 50-78-2
CAS Number: 50-78-2
Chemical Formula: C9H8O4
Synonyms:
ACETYLSALICYLIC ACID BP2000
ASPIRIN (AECTAMINOPHIN)
-Acetylsalicylic acid 2-Acetoxybenzoic acid
MOQ (Minimum Order Quantity): 1 FCL (Full Container Load)
Appearance: White crystalline
Acetylsalicylic acid CAS#50-78-2
A member of the class of benzoic acids that is salicylic acid in which the hydrogen that is attached to the phenolic hydroxy group has been replaced by an acetoxy group. A non-steroidal anti-inflammatory drug with moA cyclooxygenase inhibitor activity.Acetylsalicylic acid's original use as an analgesic, an antipyretic, and to reduce inflammation continues to this day. More recently there is some evidence that aspirin lessens the chance of heart attacks as a result of its effect as a blood "thinner."
| Acetylsalicylic acid Chemical Properties |
| Melting point | 134-136 °C (lit.) |
| Boiling point | 272.96°C (rough estimate) |
| density | 1.35 |
| refractive index | 1.4500 (estimate) |
| Fp | 250 °C |
| storage temp. | 2-8°C |
| solubility | H2O: 10 mg/mL at 37 °C |
| form | crystalline |
| color | white |
| pka | 3.5(at 25℃) |
| biological source | synthetic |
| Water Solubility | 3.3 g/L (20 ºC) |
| ε(extinction coefficient) | 190 at 298nm in aqueous base at 1mM 409 at 231nm in aqueous base at 1mM 466 at 230nm in aqueous acid at 1mM 68 at 278nm in aqueous acid at 1mM |
| Merck | 14,851 |
| BRN | 779271 |
| Exposure limits | ACGIH: TWA 5 mg/m3 NIOSH: TWA 5 mg/m3 |
| BCS Class | 3 |
| Stability: | Stable. Keep dry. Incompatible with strong oxidizing agents, strong bases, strong acids, various other compounds such as iodides, iron salts, quinine salts, etc. |
| Cosmetics Ingredients Functions | EXFOLIATING |
| InChIKey | BSYNRYMUTXBXSQ-UHFFFAOYSA-N |
| LogP | 1.190 |
| CAS DataBase Reference | 50-78-2(CAS DataBase Reference) |
| NIST Chemistry Reference | Benzoic acid, 2-(acetyloxy)-(50-78-2) |
| EPA Substance Registry System | Aspirin (50-78-2) |
| Safety Information |
| Hazard Codes | Xn |
| Risk Statements | 22-36/37/38 |
| Safety Statements | 26-36/37/39 |
| RIDADR | UN 1851 |
| OEB | B |
| OEL | TWA: 5 mg/m3 |
| WGK Germany | 1 |
| RTECS | VO0700000 |
| TSCA | Yes |
| HazardClass | 6.1 |
| PackingGroup | III |
| HS Code | 29182210 |
| Hazardous Substances Data | 50-78-2(Hazardous Substances Data) |
| Toxicity | LD50 orally in mice, rats: 1.1, 1.5 g/kg (Hart) |
Product Application of Acetylsalicylic acid CAS#50-78-2
Acetylsalicylic acid is the raw material for rodenticide intermediates 4-hydroxycoumarin.
2.Used to make outdoor structural members and equipment parts exposed in highlights, such as the automobile body, agricultural machinery parts, meters and electric lamps, road marking, etc.
3.It is the earliest applied, the most popular and the most common antipyretic analgesics anti-rheumatism medicine, has aspects of pharmacological effects as antipyretic-analgesic and anti-inflammatory, anti-platelet aggregation and works quickly and effectively. Overdosage can be easily diagnosed and treated, with rare allergic reactions. Often used to cold fever, headache, neuralgia, joint ache, muscle pain, rheumatic fever, acute wet sex arthritis, rheumatoid arthritis and toothache, etc. Listed in National Essential Medicine List. Acetylsalicylic acid also works as an intermediate of other medicines.
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