Salicylic acid CAS#69-72-7

CAS Number: 69-72-7
Chemical Formula: C7H6O3
Synonyms:

2-HYDROXYBENZOIC ACID
ACIDUM SALICYLICUM
ACETYLSALISYLIC ACID IMP C

Appearance: White Powder

MOQ (Minimum Order Quantity): 1 FCL (Full Container Load)

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Product Details

Salicylic acid CAS#69-72-7

Salicylic acid is an important organic synthetic raw material, widely used in medicine, pesticides, dyes, rubber, food and perfumes. In the pharmaceutical industry, the main drug productions of salicylic acid are sodium salicylate, wintergreen oil (methyl salicylate), aspirin (acetylsalicylic acid), salicylic acid amine, phenyl salicylate. In dye industry, it is used for production mordant pure yellow , direct yellow 3GN, direct yellow GR, direct brown 3GN, acid mordant brown G, acid mordant yellow GG, acid yellow dye complex. In pesticide production, salicylic acid is used for the synthesis of organic phosphorus pesticide Isocarbophos, intermediate isopropyl salicylate isofenphos methyl and Rodenticide warfarin, coumatetralyl intermediate 4-hydroxycoumarin. In rubber industry, it is used as anti scorching agent and production of ultraviolet absorbent and foaming agent. It is perfume material, used for the preparation of methyl salicylate, salicylic acid ethyl ester; food preservatives, its sodium Salt is mostly used, now a number of countries have been banned; methyl salicylate can be used as oral cleaning agents, such as toothpaste flavor.

Salicylic acid Chemical Properties

Melting point	158-161 °C(lit.)
Boiling point	211 °C(lit.)
bulk density	400-500kg/m3
density	1.44
vapor density	4.8 (vs air)
vapor pressure	1 mm Hg ( 114 °C)
refractive index	1,565
FEMA	3985 \| 2-HYDROXYBENZOIC ACID
Fp	157 °C
storage temp.	2-8°C
solubility	ethanol: 1 M at 20 °C, clear, colorless
form	Solid
pka	2.98(at 25℃)
color	White to off-white
PH	3.21(1 mM solution);2.57(10 mM solution);2.02(100 mM solution);
PH Range	Non0 uorescence (2.5) to dark blue 0 uorescence (4.0)
Odor	at 100.00 %. faint phenolic nutty
Odor Type	nutty
biological source	synthetic
Water Solubility	1.8 g/L (20 ºC)
λmax	210nm, 234nm, 303nm
Sensitive	Light Sensitive
Merck	14,8332
Sublimation	70 ºC
JECFA Number	958
BRN	774890
Stability:	Stable. Substances to be avoided include oxidizing agents, strong bases, iodine, fluorine. Combustible. Sensitive to light.
Major Application	Semiconductors, nanoparticles, photoresists, lubricating oils, UV absorbers, adhesive, leather, cleaner, hair dye, soaps, cosmetics, pain medication, analgesics, antibacterial agent, treatment of dandruff, hyperpigmented skin, tinea pedis, onychomycosis, osteoporosis, beriberi, fungicidal skin disease, autoimmune disease
Cosmetics Ingredients Functions	HAIR CONDITIONING ANTI-SEBORRHEIC FRAGRANCE SKIN CONDITIONING PRESERVATIVE KERATOLYTIC
InChI	1S/C7H6O3/c8-6-4-2-1-3-5(6)7(9)10/h1-4,8H,(H,9,10)
InChIKey	YGSDEFSMJLZEOE-UHFFFAOYSA-N
SMILES	OC(=O)c1ccccc1O
LogP	2.01
CAS DataBase Reference	69-72-7(CAS DataBase Reference)
NIST Chemistry Reference	Benzoic acid, 2-hydroxy-(69-72-7)
EPA Substance Registry System	Salicylic acid (69-72-7)

Safety Information

Hazard Codes	Xn,F
Risk Statements	22-41-36/37/38-36-20/21/22-11
Safety Statements	26-39-37/39-36-36/37-16
RIDADR	UN 1648 3 / PGII
WGK Germany	1
RTECS	VO0525000
Autoignition Temperature	500 °C
TSCA	TSCA listed
HS Code	29182100
Storage Class	11 - Combustible Solids
Hazard Classifications	Acute Tox. 4 Oral Eye Dam. 1 Repr. 2
Hazardous Substances Data	69-72-7(Hazardous Substances Data)
Toxicity	LD50 i.v. in mice: 500 mg/kg (Sota)

Product Application Of Salicylic acid CAS#69-72-7

Salicylic acid is widely used, eczema, psoriasis, salicylic acid can be used in acne, dandruff. The concentration of 3%~6% can be used to horny, higher than 6% of salicylic acid can damage to tissue . Below 40% of concentration is suitable for the treatment of thick cocoon, corns and warts. Salicylic acid can also be added in the treatment of acne and dandruff. Nowadays many famous cosmetic ingredients: in 1993, Clinique CLINIQUE first launched 1% salicylic acid in soft water cream, immediately became one of Clinique's most successful products; In 1998, SK-II crystal induced skin cream added 1.5%BHA ingredients to the original, and salicylic acid has effect of treatment pores and cutin like the egg peeling analogy that caused the market boom; open access Olay popular products activating cream also contains 1.5% BHA components. However, due to the high concentration of salicylic acid, it has a certain degree of damage, cosmetics containing salicylic acid concentration has generally been limited between 0.2%~1.5%, containing salicylic acid cosmetics shall be added to the note of warning signs to determine the safety of long-term use and children under 3 years of age also shall not be used.

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