Hydroxyapatite CAS#1306-06-5

CAS Number: 1306-06-5
Chemical Formula: Ca5HO13P3
Synonyms:

CALCIUM PHOSPHATE, HYDROXIDE PURIFIED
sodiumborate,monohydrate
Calcium phosphate hydroxide, Durapatite, Hydroxylapatite

Appearance: White Solid

MOQ (Minimum Order Quantity): 1 FCL (Full Container Load)

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Product Details

Hydroxyapatite CAS#1306-06-5

Calcium hydroxyapatite has a unique structure in that it is conductive along the hydroxide channels. OH- ions lie at (1/4/,1/4,1/4) and (3/4/,3/4,3/4) on the c-axis and charge-carrying protons are responsible for the observed conductivities in M10(PO4)6(OH)2. The H+ migration between the electroattractive ion (O2) to give molecular H2O in matrix channels carries charge and the resulting conductivity.
The unit cell consists of two triangular prismatic subcells forming a rhombic prism with vertical sides. There are two horizontal mirror planes at the OH levels of 1/4 and 3/4 of the c-axis. In addition, there is a center of inversion exactly in the center of each vertical face of each subcell.

Hydroxyapatite Chemical Properties

Melting point	1100 °C(lit.)
density	3.076 g/cm3(Temp: 18 °C)
storage temp.	2-8°C
solubility	H2O: 0.3 mg/mL, clear, colorless
form	solid
color	White
Water Solubility	insoluble H2O [MER06]
Merck	13,3500
Cosmetics Ingredients Functions	BULKING SKIN CONDITIONING ABRASIVE ORAL CARE
InChI	InChI=1S/2Ca.H3O4P.H2O/c;;1-5(2,3)4;/h;;(H3,1,2,3,4);1H2/q2*+2;;/p-4
InChIKey	CGMRCMMOCQYHAD-UHFFFAOYSA-J
SMILES	[Ca+2].[Ca+2].P([O-])([O-])([O-])=O.[OH-]
CAS DataBase Reference	1306-06-5(CAS DataBase Reference)
EPA Substance Registry System	Hydroxylapatite (Ca5(OH)(PO4)3) (1306-06-5)

Safety Information

Hazard Codes	Xi
Risk Statements	36/37/38
Safety Statements	26-36
WGK Germany	3
RTECS	MY8434000
F	3-10
TSCA	TSCA listed
HS Code	28352600
Storage Class	13 - Non Combustible Solids
Hazardous Substances Data	1306-06-5(Hazardous Substances Data)

Product Application of Hydroxyapatite CAS#1306-06-5

In the 1970s, it was found that sintered calcium hydroxyapatite, (Ca10(PO4)6(OH)2 (abbreviated as CaHap), possessed excellent biocompatibility and nontoxicity with femur and mandible bones. Since then, CaHap has been used as a biomaterial for artificial teeth and bones and as a filler for cements and polymers. Today, bone fillers made of CaHap are widely used in the medical and dental fields. In the 1980s, it was found that sintered CaHap has a good compatibility with skin tissues. Hence, percutaneous devices based on CaHap have been developed and applications have included continuous ambulatory peritoneal dialysis and intravenous hyperalimentation systems, blood pressure measurement and blood access for nutrition. Recently, many researchers have studied the chemistry of apatites, particularly CaHap, and have found various applications, such as artificial teeth and bones, ion exchangers, adsorbents for chromatography to separate proteins and enzymes, catalysts, ionic conductors, temperature and gas sensors, etc.

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